Screening of Potent Anti-dementia Acetylcholinesterase Inhibitor-containing Edible Mushroom Pholiota adiposa and the Optimal Extraction Conditions for the Acetylcholinesterase Inhibitor
To develop a new anti-dementia acetylcholinesterase (AChE) inhibitor from edible mushrooms, AChE inhibitory activities were determined on water and ethanol extracts of various edible mushrooms from oriental medicine markets and agriculture markets. As a result, the 70% ethanol extract from Pholiota...
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Published in | Hangug gynnhaghoi ji Vol. 44; no. 4; pp. 314 - 317 |
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Main Authors | , , , |
Format | Journal Article |
Language | Korean |
Published |
한국균학회
31.12.2016
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Subjects | |
Online Access | Get full text |
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Summary: | To develop a new anti-dementia acetylcholinesterase (AChE) inhibitor from edible mushrooms, AChE inhibitory activities were determined on water and ethanol extracts of various edible mushrooms from oriental medicine markets and agriculture markets. As a result, the 70% ethanol extract from Pholiota adiposa fruiting body had the highest AChE inhibitory activity of 30.6, and its water extract also had an AChE inhibitory activity of 23.8%. Therefore, we finally selected P. adiposa as a potent anti-dementia AChE inhibitor-containing mushroom. The AChE inhibitor of P. adiposa was maximally extracted when its fruiting body was treated with water for 3hr at 70oC and 70% ethanol for 12 hr at 70oC, respectively. |
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Bibliography: | The Korean Society of Mycology KISTI1.1003/JNL.JAKO201609636669569 |
ISSN: | 0253-651X 2383-5249 |