도인(桃仁) 껍질의 화장품약리활성 및 항염 효과

• Published in: 大韓本草學會誌 Vol. 21; no. 2; pp. 87 - 93
• Main Authors: 조우아, Woo A Joe, 장민정, Min Jung Jang, 천순주, Soon Ju Cheon, 성지연, Ji Yeun Sung, 최은영, Eun Young Choi, 강보연, Bo Yeon Kang, 정수현, Su Hyun Jung, 정연숙, Yeun Suck Jeung, 김영선, Young Sun Kim, 안봉전, Bong Jeun An, 이창언, Chang Eon Lee
• Format: Journal Article
• Language: Korean
• Published: 대한본초학회 30.06.2006
• Subjects: Anti-inflammatory effects; Cosmeceutical activity; Persicae semen; Persicae semen; Cosmeceutical activity; Anti-inflanmmatory effects
• ISSN: 1229-1765

Objectives : In this paper, we tested the applicability of shell from Persicae semen in cosmetics through cosmeceutical activities including anti-oxidant, tyrosinase inhibition and anti-inflammatory effects. Methods : Persicae semen, which had been extracted, concentrated, and freeze drying with water and ethanol, have been used for the experiment. The effects on electronic donating ability, SOD-like activity, xanthine oxidase inhibition, whitening effect have been investigated in the cosmeceutical activity measurement of function experiment. Results : In the electron donating ability test, 1,000ppm of EPS (ethanol extract of shell from Persicae semen) showed an effect of 87%. SOD-like activities showed 93% at the 10,000ppm of WPS (water extract of shell from Persicae semen). In the xanthine oxidase inhibition test, 1,000ppm of BHA showed an effect of 27%, while EPS showed an effect of 62%. We were able to get an effect of 95% from EPS at 10,000 ppm in the tyrosinase inhibition test. In the anti-inflammatory test, the EPS inhibited the generation of nitric oxide. In the case of the EPS, there were no signs of cytotoxicity against raw 264.7 and anti-inflammatory effects could be identified when the manifestation of iNOS was decreased. Conclusion : Therefore, the EPS has potential as an effective raw materials for cosmetic.