Study on the Relationship between the Structure and Antioxidant Activities of Chalcones

The purpose of this study is to examine the relationship between antioxidant activities and chemical structures of various chalcones. Twenty-two chalcones were assessed for their radical scavenging activity using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Of 22 compounds tested, the most active...

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Bibliographic Details
Published in목재공학 Vol. 34; no. 2; pp. 88 - 94
Main Authors Park, Youngki, Lee, Hak-Ju, Lee, Wi Young, Ahn, Jin-Kwon, Hwang, Byung-Ho
Format Journal Article
LanguageKorean
Published 한국목재공학회 20.03.2006
Subjects
antioxidant activity
chalcone
structure-activity relationships
chalcone
structure-activity relationships
antioxidant activity
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Summary:The purpose of this study is to examine the relationship between antioxidant activities and chemical structures of various chalcones. Twenty-two chalcones were assessed for their radical scavenging activity using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Of 22 compounds tested, the most active on DPPH radical was 2',4-dihydroxy-3,3'5-trimethoxy-5'-propylchacone (4) (72.6% at 100 ppm). It was followed by 3',4'-dihydroxy-3,4,5-trimethoxy-6'-methylchalcone (6), 2',4,4'-trihydroxy-3-methoxy-5-propenylchalcone (7) and 2',4,4'-trihydroxy-3,5-dimethoxychalcone (13). Based on the results, we concluded that the scavenging activity is controlled by the number and the position of the substitution in the compound.
Bibliography:The Korean Society of Wood Science & Technology
KISTI1.1003/JNL.JAKO200610103490915
ISSN:1017-0715