국내산 곽향(藿香)의 품질관리 연구

• Published in: 大韓本草學會誌 Vol. 34; no. 2; pp. 67 - 74
• Main Authors: 한민우, Min Woo Han, 박채규, Chae Kyu Park, 박철수, Chul Su Park, 안희준, Hee Jun Ahn, 서정범, Jeong Bum Seo, 이영종, Young Jong Lee
• Format: Journal Article
• Language: Korean
• Published: 대한본초학회 31.03.2019
• Subjects: Acacetin; Agastachis herba; Agastachoside; Quality Control; Tilianin; TLC; TLC; Agastachis herba; Tilianin; Acacetin; Agastachoside; Quality Control
• ISSN: 1229-1765

Objectives : Agastachis herba is a aerial part of Agastache rugosa (Fischer et Meyer) O. Kuntze which has been used as traditional medicines. Methods : The samples were collected using a domestic cultivation of Agastachis Herba. We experiment on essential oil content, the content of ethanol soluble extracts and HPLC profiling. Results : Loss on drying of Agastachis Herba contents of harvest in June ~ July was 4.93~8.26% and contents of harvest in August ~ September was 3.88~5.38%. Ash of Agastachis Herba contents of harvest in June ~ July was 5.07~7.97% and contents of harvest in August ~ September was 4.55~7.61%. Acid-insoluble ash of Agastachis Herba contents of harvest in June ~ July was 0.43~1.62% and contents of harvest in August ~ September was 0.46~1.44%. Essential oil contents of Agastachis Herba contents of harvest in June ~ July was 0.2~0.4 ㎖ and contents of harvest in August ~ September was 0.2~0.6 ㎖. Ethanol soluble extracts of Agastachis Herba contents of harvest in June ~ July was 9.72~20.44% and contents of harvest in August ~ September was 11.00~18.70%. HPLC profiling was detected of tilianin(12.93 min), acacetin(15.84 min) and agastachoside(17.95 min). Conclusion : Agastachis Herba should be harvested from August ~ September, the time of flowering. This is because of the high content of active compounds.1)