상지(桑枝)가 흰쥐의 혈압 및 Streptozotocin유발 당뇨에 미치는 영향

Objecitivies : This study was performed to prove the anti-hypertensive and anti-diabetic effect of Mori Ramulus(MR). Methods : The examination was done on the femoral artery occlusion of the rat, and check the blood pressure. In addition, we observed therapueutic effects on diabetes rats induced by...

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Published in大韓本草學會誌 Vol. 23; no. 2; pp. 203 - 212
Main Authors 함인혜, In Hye Ham, 정은식, Eun Sik Jeong, 이병희, Byong Hee Lee, 최호영, Ho Young Choi
Format Journal Article
LanguageKorean
Published 대한본초학회 30.06.2008
Subjects
DNA analysis
hypotensive effect
Scrophularia buergeriana
Scrophularia buergeriana
hypotensive effect
DNA analysis
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Summary:Objecitivies : This study was performed to prove the anti-hypertensive and anti-diabetic effect of Mori Ramulus(MR). Methods : The examination was done on the femoral artery occlusion of the rat, and check the blood pressure. In addition, we observed therapueutic effects on diabetes rats induced by streptozotocin. Results : MR MeOH Ex. showed few effect on descending blood pressure in SD rat model. MR CHCl3 layer (MRC) showed significant effect on descending blood pressure. MR was effective on the streptozotocin-induced diabetes SD rats. Especially MRC reduced the amount of serum glucose, BUN, triglyceride and insulin level. Conclusions : MRC could induce descending blood pressure in the rat model. Also, it is expected to be effective in diabetes treatment.
Bibliography:The Korea Association of Herbology
KISTI1.1003/JNL.JAKO200831049577753
ISSN:1229-1765