호흡기 바이러스 감염과 C-Reactive Protein

• Published in: Korean journal of clinical laboratory science Vol. 49; no. 1; pp. 15 - 21
• Main Authors: 전재식, Jae-sik Jeon, 임인수, Insoo Rheem, 김재경, Jae Kyung Kim
• Format: Journal Article
• Language: Korean
• Published: 대한임상검사과학회 30.03.2017
• Subjects: C-Reactive Protein; Coinfection; Length of stay; Respiratory virus; Virus diseases; Virus diseases; Respiratory virus; Coinfection; C-Reactive Protein; Length of stay
• ISSN: 1738-3544; 2288-1662

C-reactive protein (CRP) levels are not generally associated with viral infections. This study investigated the changes in the CRP level caused by an infection from respiratory virus (RV). Nasopharyngeal samples from hospitalized patients with suspected RV infection were used to measure the CRP levels, virus load, virus-virus co-infection, age, sex, and length of hospital stay (LOS). Abnormal CRP levels were detected in 62.3% (3,608 out of 5,788) of all RV-positive samples. The percentage of patients with abnormal CRP levels tended to increase with age. Furthermore, LOS in patients with abnormal CRP levels was significantly longer than that in patients with normal CRP levels. The frequency of elevated CRP levels differed according to the causative virus and the frequency of abnormal levels increased with age. Moreover, LOS was longer in those with abnormal CRP levels. These data provide important insights into the role of CRP levels in RV infection.