요양보호시설 이용중인 알츠하이머 치매환자의 구강 병원성 미생물 분석

• Published in: Han'guk Ch'iwisaeng Hakhoe chi Vol. 22; no. 5; pp. 411 - 416
• Main Authors: 정서윤, Seo-yun Jung, 정미애, Mi-ae Jeong, 김춘성, Chun-sung Kim, 김수관, Su-gwan Kim
• Format: Journal Article
• Language: Korean
• Published: 한국치위생학회 30.10.2022
• Subjects: Alzheimer; Cognitive impairment; Degenerative neurological disease; Dementia; Pathogenic microorganisms; 병원성 미생물; 알츠하이머; 인지장애; 치매; 퇴행성 신경질환
• ISSN: 2287-1705; 2288-2294

Objectives: This study aimed to identify pathogenic microorganisms in the oral cavity of Alzheimer’s dementia patients and recognize the necessity and importance of oral prevention management. Methods: The participants comprised 40 dementia patients aged 60 years or older and general patients who were using nursing care facilities in Gwangju from February to July 2017. Samples were collected with Eazyperio products for oral pathogenic microbial testing. Eighteen types of bacteria could be detected by analyzing Multiplex-Quantity Real Time polymerase chain reaction at a genetic testing agency. Results: The study comprised more women than men. Most participants were in their 80s. Statistically significant differences were observed in some oral pathogenic microorganisms. Conclusions: Pathogenic microorganisms could more easily proliferate in the oral cavities of Alzheimer’s dementia patients than they could among general elderly participants due to a lack of awareness of oral hygiene and prevention management. To improve this, it is considered necessary to deploy oral health care professionals.