락토페린이 국내분리 유아 로타바이러스의 MA 104세포 감염에 미치는 영향

It has long been known that lactoferrin prevents human beings from infection of virus. To prove this activity of lactoferrin, we evaluated the activities of different lactoferrins to an isolate human rotavirus K-21. Bovine lactoferrin inhibited infection of K-21 to MA-104 cell at the concentration o...

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Published inJournal of bacteriology and virology Vol. 29; no. 2; pp. 87 - 98
Main Authors 차광종, Gwang Jong Cha, 유대열, Dae Yeol Yoo, 이종기, Jong Gee Lee, 유제현, Je Hyun Yoo
Format Journal Article
LanguageKorean
Published 대한바이러스학회 30.06.1999
Subjects
Digestive enzymes
Human rotavirus
Hydrolysed Lactoferrin
Lactoferrin
Lactoferrin
Digestive enzymes
Human rotavirus
Hydrolysed Lactoferrin
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Summary:It has long been known that lactoferrin prevents human beings from infection of virus. To prove this activity of lactoferrin, we evaluated the activities of different lactoferrins to an isolate human rotavirus K-21. Bovine lactoferrin inhibited infection of K-21 to MA-104 cell at the concentration of 25.9 ㎛ whereas bovine hydrolysed lactoferrin prevented rotavirus infection at 103.8 ㎛. However human lactoferrin prevented infection of K-21 at the concentration of 217.5 ㎛. These data suggested that lactoferrin activity may be unaffected by the intestinal digestive enzymes and bovine lactoferrin is more active than human lactoferrin with respect to prevention of rotavirus infection.
Bibliography:The Korean Society of Virology
ISSN:1598-2467
2093-0429