1998년 1월부터 9월사이에 발생한 Malaria 의 임상적 고찰

• Published in: The Korean journal of medicine Vol. 56; no. 4; pp. 517 - 525
• Main Authors: 김용훈, Yong Hoon Kim, 곽현진, Hyun Jin Kwak, 정홍배, Hong Bae Jeong, 안명수, Myoung Soo Ahn, 남홍우, Hong Woo Nam, 이홍순, Hong Soon Lee, 유수웅, Soo Wong Yoo, 정예경, Ye Kyeong Jeong, 이성은, Seong Eun Lee
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 01.04.1999
• Subjects: Imported malaria; Indigenous malaria; Plasmodium vivax; Relapse
• ISSN: 1738-9364

Objective : Annually, the prevalence of indigenous and imported malarial infections is steadily increasing since 1993 in Korea. In order to understand the current characteristics of malarial infections and to prevent, the present research reviewed twenty-seven cases between January and September 1998. Method : In this study, all the twenty-seven (twenty- six patients) cases were obtained from admitted patients between January and September 1998. We had performed routine blood chemical studies, peripheral blood thin and thick smear, physical examination and abdominal sonography. Any patient with a previous history of a narcotic drug injection or had blood transfusion was excluded. Results : Twenty cases (74.1%) were indigenous and seven (25.9%) were imported malaria. Yeonchon-Gun (nine cases) was the most prevalent area in the indigenous cases; Cambodia (three cases) were the most one in the imported cases. Peripheral blood thin smear revealed Plasmodium vivax in all (100%) indigenous malaria, while four cases (57.1%) were P. vivax and one (14.3%) was P. falciparum and two (28.6%) were mixed infections with P. vivax and P. falciparum in the imported cases. In a 3-month period between July and September, peak prevalence (80.4%) was observed. The negative conversion of peripheral blood smear was achieved much earlier in the indigenous (3.9±1.4day) than in the imported (5.7±1.9day) after the treatment but, was not statistically signifcant. Conclusion : Plasmodium ovale was the only unique causative species in the indigenous malaria. Also Yeonchon-Gun and Cheolwon-Gun had been the most important endemic areas as previous reports. One relapse case had been occurred in the imported malaria. On the basis of our data, more efforts for control of malaria should be necessary for eradication and prevention of indigenous and imported malarial infections in Korea.