수영과 저출력 레이저 치료가 류마티스 관절염 흰쥐의 혈청 인터루킨-6 농도에 미치는 영향

• Published in: Han'guk Chŏnmun Mulli Ch'iryo Hakhoe chi = Journal of the Korean Academy of University Trained Physical Therapists Vol. 15; no. 1; pp. 69 - 76
• Main Authors: 박미희, Mi Hee Park, 노민희, Min Hee Rho, 이현옥, Hyun Ok Lee, 구봉오, Bong Oh Koo, 황수명, Soo Myung Hwang
• Format: Journal Article
• Language: Korean
• Published: 한국전문물리치료학회 28.02.2008; Korean Academy Of University Trained Physical Therapy
• Subjects: Hind paw thickness; Interleukin 6; Laser; Rheumatoid arthritis; Space of knee joint; Swimming; 물리치료학; Hind paw thickness; Swimming; Space of knee joint; Rheumatoid arthritis; Laser; Interleukin-6
• ISSN: 1225-8962; 2287-982X

This study was designed to determine the effects of swimming and low power laser on rheumatoid arthritis in Sprague-Dawley rats. Rheumatoid arthritis was induced in 36 rats among 48 Sprague-Dawley rats by the subcutaneous injection of .05 $m{\ell}$ Freund's Complete Adjuvant into the right hind paw and .05 $m{\ell}$ Freund's Complete Adjuvant into the right hind knee joint capsule. A second injection was performed by the same method using .1 $m{\ell}$ Freund's Complete Adjuvant per a rat. Arthritic rats were divided into 8 groups: each 1 week and 2 weeks of arthritic swimming, arthritic laser, arthritic case control and normal group. In this study, several experimental tests were performed to determine the concentration of Interleukin-6, the space of the knee joint and the thickness of the hind paw. The concentration of Interleukin-6 and hind paw thickness decreased in the swimming group and laser group as compared to the control group. The space of the knee joint increased significantly after the swimming exercise. Swimming and low power laser therapy positively affect rheumatoid arthritis in rats affect by decreasing the concentration of Interleukin-6 and hind paw thickness, and increasing the space of the knee joint.