Two cases of pleuroplumonary blastoma

• Published in: The Journal of the Japanese Association for Chest Surgery Vol. 28; no. 5; pp. 662 - 667
• Main Authors: Yamamoto, Kozo, Kai, Hiroki, Hirose, Ryuichiro, Yamashita, Shin-ichi, Shiraishi, Takeshi, Iwasaki, Akinori
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Association for Chest Surgery 15.07.2014
• Subjects: pleuropulmonary blastoma
• ISSN: 0919-0945; 1881-4158
• DOI: 10.2995/jacsurg.28.662

Pleuropulmonary blastoma is a rare malignant neoplasm of childhood. Tumors can arise from the lung, pleura, or both sites. The standard treatment is surgical resection. The value of chemotherapy and radiotherapy has not yet been evaluated because of the rarity of the disease. Despite aggressive treatment, pulmonary blastoma is still associated with a poor prognosis. Case 1: A four-year-old female with a cough and hemoptysis was admitted to our hospital. Chest CT showed a tumor measuring 7.0 cm at the right lower lobe. Right lower lobectomy was performed. The patient was diagnosed with pleuropulmonary blastoma Type III, and chemotherapy was initiated after surgical treatment. Nine months after surgery, two brain metastases were found and removed surgically. Case 2: A four-year-old female with a cough, fever, and left-sided chest pain was admitted to our hospital. Chest CT showed a large tumor filling the left hemithorax. Left upper lobectomy was performed. The patient was diagnosed with pleuropulmonary blastoma Type II. After surgery, chemotherapy was initiated, and there has been no recurrence during the 10 months since the procedure.