Pregnancy and soluble VEGF receptor 1(sFlt-1)

• Published in: Reproductive Immunology and Biology Vol. 34; pp. 9 - 16
• Main Authors: Kumasawa, Keiichi, Iriyama, Takayuki, Nagamatsu, Takeshi, Osuga, Yutaka, Fujii, Tomoyuki
• Format: Journal Article
• Language: Japanese
• Published: Japan Society for Immunology of Reproduction 2019

Hypertensive disorders of pregnancy (HDP) are still life-threatening diseases.However, the pathogenesis of HDP has progressed rapidly in the last 20 years. Recently ‘Two Step Theory’ has been proposed and widely accepted. In the theory, soluble VEGF receptor 1(sFlt-1) plays crucial roles. Thus far,...