Cellular balance of glutathione levels through the expression of γ-glutamylcysteine synthetase and glutathione thiol transferase genes in human hepatic cells resistant to a glutathione poison

• Published in: Biochimica et Biophysica Acta (BBA) - General Subjects Vol. 1427; pp. 367 - 377
• Main Authors: Toshiya Tanaka, Minoru Nomoto, Kazuto Nishio, Takeshi Uchiumi, Takahito Kondo, Kimitoshi Kohno, Nagahiro Saijo, Michihiko Kuwano
• Format: Journal Article
• Language: Japanese
• Published: Elsevier BV 01.05.1999
• Subjects: Buthionine Sulfoximine; Drug Resistance; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Humans; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Transfection; Tumor Cells, Cultured