Cellular balance of glutathione levels through the expression of γ-glutamylcysteine synthetase and glutathione thiol transferase genes in human hepatic cells resistant to a glutathione poison

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Bibliographic Details
Published inBiochimica et Biophysica Acta (BBA) - General Subjects Vol. 1427; pp. 367 - 377
Main Authors Toshiya Tanaka, Minoru Nomoto, Kazuto Nishio, Takeshi Uchiumi, Takahito Kondo, Kimitoshi Kohno, Nagahiro Saijo, Michihiko Kuwano
Format Journal Article
LanguageJapanese
Published Elsevier BV 01.05.1999
Subjects
Buthionine Sulfoximine
Drug Resistance
Gene Expression Regulation
Glutamate-Cysteine Ligase
Glutathione
Glutathione Peroxidase
Glutathione Transferase
Humans
Promoter Regions, Genetic
Proto-Oncogene Proteins c-fos
Proto-Oncogene Proteins c-jun
RNA, Messenger
Transfection
Tumor Cells, Cultured
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ISSN:0304-4165
DOI:10.1016/s0304-4165(99)00016-1