A Case of Thirty-months' Survival with No Recurrence of Ascending Colon Mixed Adenoneuroendocrine Carcinoma after Laparoscopic Surgery and Adjuvant Chemotherapy

A 48-year-old man was referred to our hospital because of fecal occult blood. Colonoscopy showed a type 3 tumor in the ascending colon. A biopsy revealed well or moderately-differentiated adenocarcinoma. Laparoscopic right hemi-colectomy and lymphadenectomy were performed. Histopathologically, neuro...

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Published inNihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 78; no. 6; pp. 1326 - 1331
Main Authors MII, Yasuhiko, KOHAMA, Takuya, URADE, Takeshi, MURATA, Kouichi, SAWA, Hidehiro, KURODA, Daisuke
Format Journal Article
LanguageJapanese
Published Japan Surgical Association 2017
Subjects
adjuvant chemotherapy
ascending colon MANEC
laparoscopic surgery
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Summary:A 48-year-old man was referred to our hospital because of fecal occult blood. Colonoscopy showed a type 3 tumor in the ascending colon. A biopsy revealed well or moderately-differentiated adenocarcinoma. Laparoscopic right hemi-colectomy and lymphadenectomy were performed. Histopathologically, neuroendocrine carcinoma and adenocarcinoma were found in the tumor, and each carcinoma accounted for more than 30% of the tumor. The diagnosis was mixed adenoneuroendocrine carcinoma (MANEC). After the operation, adjuvant chemotherapy (cisplatin+etoposide) was performed. At 30-month follow-up, the patient was well with no recurrence. Survival for more than 2 years after surgery for colonic MANEC is rare. We report this case with a review of the literature.
ISSN:1345-2843
1882-5133
DOI:10.3919/jjsa.78.1326