The Effects of M-protein Fraction of Hemolytic Streptococci on Embryonic Heart in the Rat : THE 9th CONFERENCE ON PREVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE

• Published in: JAPANESE CIRCULATION JOURNAL Vol. 49; no. 12; pp. 1265 - 1267
• Main Authors: MIYATA, KOICHIRO, JITOSHO, TAMOTSU, TAKESUE, TETSUO, MUNAKATA, SHUZO, ONO, SEIGO, YAMAMOTO, EIJI, KAWAKAMI, KIYOSHI, TERAWAKI, TAMOTSU
• Format: Journal Article
• Language: English
• Published: The Japanese Circulation Society 20.12.1985
• Subjects: Cardiovasucular malformations; Experimental teratology; M-protein of hemolytic streptococci

Wistar rats were administered M-protein fraction (MP) of group A type 12 hemolytic streptococci on day 9 of gestation. When 9 mg/kg of MP was injected, the incidence of malformations was 11.8%, and the incidence of cardiovascular malformations was 7.9%. The main malformations were ventricular septal...