Severe Masculinization of Urogenital Organs with Hypospadias in a Freemartin Holstein Calf
A freemartin of Holstein calf (7 months old) accompanied with penile hypospadias was clinically investigated and a pair of testis-like tissue was extracted from the subcutaneous thigh. Sex chromosomal analyses showed XX/XY chimeras in the blood, whereas the XX female type was present in the kidney a...
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Published in | Journal of the Japan Veterinary Medical Association Vol. 64; no. 6; pp. 461 - 463 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
Japan Veterinary Medical Association
20.06.2011
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Subjects | |
Online Access | Get full text |
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Summary: | A freemartin of Holstein calf (7 months old) accompanied with penile hypospadias was clinically investigated and a pair of testis-like tissue was extracted from the subcutaneous thigh. Sex chromosomal analyses showed XX/XY chimeras in the blood, whereas the XX female type was present in the kidney and spleen. Pathological examination revealed the marked spongy body of the penis, prostate gland, and vesicular gland, whereas the female gonad and müllerian duct remained as rudimentary funiculi. These findings suggested that the calf was a freemartin with hypospadias and ectopic testicles in a morphological anomaly of the urinary tracts with severe masculinization. |
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ISSN: | 0446-6454 2186-0211 |
DOI: | 10.12935/jvma.64.461 |