The Relationship Between Remnant-like Particle(RLP)Cholesterol and Insulin Resistance

• Published in: Official Journal of the Japanese Society of Human Dry Dock Vol. 18; no. 1; pp. 38 - 41
• Main Authors: Nonaka, Yasunobu, Iizuka, Tetsuji, Mukaiyama, Reiko
• Format: Journal Article
• Language: Japanese
• Published: JAPAN SOCIETY OF NINGEN DOCK 30.06.2003; 公益社団法人 日本人間ドック学会
• Subjects: insulin resistance; remnant-like particle lipoprotein (RLP) cholesterol; インスリン抵抗性; レムナント様リポ蛋白コレステロール(RLP-C)
• ISSN: 0914-0328; 2186-5019
• DOI: 10.11320/ningendock1986.18.38

We investigated the relationship between insulin resistance and remnant-like particle lipoprotein (RLP) cholesterol levels in middle-aged males with normal blood pressure and total cholesterol (TC) and triglyceride (TG) levels. Insulin resistance was evaluated with homeostasis model assessment-insulin resistance (HOMA-IR). The subjects were divided into two groups; normal glucose tolerance (NGT) and impaired glucose tolerance (IGT) according to their fasting blood glucose levels. It was found that in the NGT group there was a correlation between HOMA-IRan d triglyceride>high density lipoprotein(HDL)cholesterol>RLP cholesterol. In the IGT group there was a correlation between HOMA-IR and total cholesterol>RLP cholesterol. When fasting blood glucose was normal or slightly increased there was a correlation between HOMA-IRan d RLP cholesterol, and it was noted that RLP cholesterol is a good marker for insulin resistance.