Usefulness of magnifying endoscopy with narrow band imaging for diagnosis of gastric epithelial tumors in patients with familial adenomatous polyposis

• Published in: Progress of Digestive Endoscopy Vol. 85; no. 1; pp. 36 - 39
• Main Authors: Miyamoto, Yuji, Yamamoto, Yorimasa, Osumi, Hiroki, Taniguchi, Chika, Tomida, Hideomi, Morishige, Kenjiro, Horiuchi, Yusuke, Ishikawa, Hirotaka, Yoshizawa, Natsuko, Omae, Masami, Hirasawa, Toshiaki, Yoshio, Toshiyuki, Ishiyama, Akiyoshi, Tsuchida, Tomohiro, Fujisaki, Junko, Igarashi, Masahiro
• Format: Journal Article
• Language: Japanese
• Published: Japan Gastroenterological Endoscopy Society Kanto Chapter 06.12.2014
• Subjects: FAP; NBI
• ISSN: 1348-9844; 2187-4999
• DOI: 10.11641/pde.85.1_36

Familial adenomatous polyposis (FAP) manifests occasionally as a gastric epithelial tumor. It is important to diagnose the tumor at an early stage for less invasive treatment. In this study, we examined the usefulness of magnifying endoscopy with narrow-band imaging (ME-NBI) for examining gastric epithelial tumors in patients with FAP. Four FAP patients with gastric epithelial tumors underwent ME-NBI and subsequently, endoscopic resection of the lesions. There were 8 lesions (3 adenoma, 5 cancer) in the four patients. We enrolled these patients into the present retrospective study. We analyzed the ME-NBI findings using the 'VS classification system’ and compared them with the pathological findings after endoscopic resection. A demarcation line was observed clearly in all the lesions, and an irregular vascular pattern was recognized in all the cancer lesions. Two of the 3 adenoma lesions had regular microvascular and microsurface patterns. There was only 1 lesion in which the ME-NBI findings did not match the pathological findings. Thus, the concordance rate between the ME-NBI findings using the VS classification and the pathological findings was 87.5%. Although there are some limitations of this study, we think that ME-NBI for FAP patients with gastric epithelial tumors is useful for establishing a qualitative diagnosis.