Does neoadjuvant chemotherapy increase the incidence of postoperative complication for gastric cancer surgery?

Neoadjuvant chemotherapy for gastric cancer is not associated with high incidence of postoperative complications from the results of randomized controlled clinical trials carried out in Western countries and Japan. Similar findings were drawn from literature review of retrospective cohorts. However,...

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Bibliographic Details
Published inJournal of Japan Society for Surgical Infection Vol. 16; no. 2; pp. 118 - 125
Main Authors Fukagawa, Takeo, Horikawa, Masahiro, Kiyokawa, Takashi, Soeda, Naruyoshi, Kumata, Yoshimasa, Fukushima, Ryoji
Format Journal Article
LanguageJapanese
Published Japan Society for Surgical Infection 30.04.2019
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Summary:Neoadjuvant chemotherapy for gastric cancer is not associated with high incidence of postoperative complications from the results of randomized controlled clinical trials carried out in Western countries and Japan. Similar findings were drawn from literature review of retrospective cohorts. However, as the frailty of patient background, combination chemotherapy with multiple agents, severe toxicity caused by chemotherapy and extensive surgery may affect the incidence of postoperative complication, surgery after neoadjuvant chemotherapy should be done carefully in case with those factors.
ISSN:1349-5755
2434-0103
DOI:10.24679/gekakansen.16.2_118