Invasive pneumococcal disease due to non-vaccine serotype 10A Streptococcus pneumoniae in an infant

We report the case of a 2-month-old boy who was hospitalized due to fever after a single administration of the 13-valent pneumococcal conjugate vaccine (PCV13) and subsequently diagnosed with invasive pneumococcal disease (IPD). Blood culture identified Streptococcus pneumoniae serotype 10A, a non-P...

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Published inJAPANESE JOURNAL OF HOSPITAL GENERAL MEDICINE Vol. 19; no. 3; pp. 203 - 207
Main Authors Matsuhashi, Kazuhiko, Ohne, Marina, Abe, Yoshifusa, Kamijo, Kaori, Honda, Kana, Yoshida, Yurika, Kanazawa, Takeru, Suitou, Tatsuya
Format Journal Article
LanguageJapanese
Published JAPAN SOCIETY OF HOSPITAL GENERAL MEDICINE 31.05.2023
一般社団法人 日本病院総合診療医学会
Subjects
10A
13-valent pneumococcal conjugate vaccine
13価肺炎球菌結合型ワクチン
Streptococcus pneumoniae
肺炎球菌
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ISSN2185-8136
2758-7878
DOI10.60227/jhgmwabun.19.3_203

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Summary:We report the case of a 2-month-old boy who was hospitalized due to fever after a single administration of the 13-valent pneumococcal conjugate vaccine (PCV13) and subsequently diagnosed with invasive pneumococcal disease (IPD). Blood culture identified Streptococcus pneumoniae serotype 10A, a non-PCV13 serotype. Despite a significant decline in the number of children with IPD after the introduction of PCV13, the rate of IPD due to non-PCV13 serotypes has increased. Pneumococcal vaccination cannot completely prevent IPD, and IPD due to non-vaccine serotypes should be considered in children with fever.
ISSN:2185-8136
2758-7878
DOI:10.60227/jhgmwabun.19.3_203