Evaluation of the efficacy of cefmenoxime (CMX) in maxillary sinus instillation therapy for sinusitis

• Published in: jibi to rinsho Vol. 37; no. 4; pp. 833 - 850
• Main Authors: BABA, Shukichi, KOBAYASHI, Takehiro, ITO, Haruo, UNNO, Tokuji, NAGANO, Etsuji, SAKAMOTO, Nobuo, TAKASAKA, Tomonori, SUZUKI, Mamoru, ENDO, Satomi, SAKURADA, Takashi, KAWAMURA, Shozo, ICHIKAWA, Ginichiro, UEHARA, Nobuo, ETO, Atsuko, KOMATSUZAKI, Atsushi, NOMURA, Toshiyuki, TANINO, Toru, ISHII, Tetsuo, TAKAYAMA, Mikiko, MIYAKE, Hirosato, SHINKAWA, Atsusi, KIMURA, Hidenari, MARUO, Takeshi, TONAI, Akira, INAGAKI, Mitsuaki, SAITO, Hitoshi, FUJIEDA, Shigeharu, SAKAKURA, Yasuo, MAJIMA, Yuichi, MASUDA, Sawako, SAKAKURA, Kenji, HAMAGUCHI, Fumi, KUBO, Masahiko, MURAKAMI, Yasushi, TAKEIAKA, Hiroshi, TOYODA, Kenji, MATSUNAGA, Toru, OGINO, Satoshi, SHIRAISHI, Takayuki, ISHIDA, Minoru, KIMU, Seijin, ITO, Masato, SASAKI, Ryoji, HAGA, Minoru, HARADA, Yasuo, TAGASHIRA, Nobuharu, HIRAKAWA, Katsuhiro, SEKITANI, Toru, INOKUMA, Tetsuhiko, KANESADA, Keiko, HIRATA, Tetsuyasu, MOGI, Goro, KURONO, Yuichi, BUNDO, Junichi, YYAMA, Masaru, SHIMA, Tetsuya, HIROTA, Rikako, FUKAMI, Kozo, MATSUZAKI, Tsutomu, DEGUCHI, Koichi
• Format: Journal Article
• Language: Japanese
• Published: JIBI TO RINSHO KAI 20.07.1991
• Subjects: Cefmenoxime
• ISSN: 0447-7227; 2185-1034
• DOI: 10.11334/jibi1954.37.4_833

A multi-institutional study of CMX maxillary sinus instillation therapy in the treatment of sinusitis was conducted in accordance with a uniform protocol. The following results were obtained. 1. The rate of clinical efficacy (good and excellent ratings combined) was as high as 83.3% according to the doctors in charge and 81.1% according to the committee. 2. The efficacy rate based on X-ray findings was 60.3% according to the doctors and 59.3% according to the committee. 3. The bacteriological response was excellent with an elimination rate of 87.1%. 4. In 140 cases assessed for antibiotic safety, no side effects were reported. The above results suggest that CMX administered nasally is beneficial in the local treatment of sinusitis.