Application of ICG fluorescence endoscope for the diagnosis of acute rejection of intestinal transplantation

Rejection is one of the major obstacles for the successful intestinal transplantation(ITx). In this study, we applied a new indocyanine green(ICG)fluorescence endoscope to a large animal ITx model. We performed swine heterotopic segmental ITx, and visualized mural vascular structure of the intestina...

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Bibliographic Details
Published inOrgan Biology Vol. 19; no. 1; pp. 36 - 40
Main Authors Sakamoto, Seisuke, Shigeta, Takanobu, Enosawa, Shin, Nakazawa, Atsuko, Chiba, Toshio, Kasahara, Mureo
Format Journal Article
LanguageJapanese
Published The Japan Society for Organ Preservation and Biology 10.07.2012
Subjects
ICG fluorescent endoscope
microcirculation
rejection
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Summary:Rejection is one of the major obstacles for the successful intestinal transplantation(ITx). In this study, we applied a new indocyanine green(ICG)fluorescence endoscope to a large animal ITx model. We performed swine heterotopic segmental ITx, and visualized mural vascular structure of the intestinal graft at various grade of acute rejection by the ICG fluorescence endoscope. The endoscopic findings revealed that the disarray and irregularity of the vascular structure worsened with increased grade of acute rejection. Clinical application of this new endoscopic evaluation for rejection in ITx is promising.
ISSN:1340-5152
2188-0204
DOI:10.11378/organbio.19.36