The role of suture materials in small vascular anastomosis

Vascular grafts were implanted in the abdominal aorta of 39 adult mongrel dogs (14.07±3.24kg) using synthetic absorbable suture materials, that is polygiycolic acid (PGA) and polydioxanon (PDS), and nonabsorbable polypropylene (PP) as a control. The macroscopic findings and the histologic examinatio...

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Published inJinko Zoki Vol. 14; no. 2; pp. 971 - 974
Main Authors SATO A., KUBO Y., SASAJIMA T., INABA M., IZUMI U., MORIMOTO N., KOKUBO M., SAKAI H., NAKAYAMA K., SANEJIMA N.
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本人工臓器学会 1985
JAPANESE SOCIETY FOR ARTIFICIAL ORGANS
Subjects
Online AccessGet full text
ISSN0300-0818
1883-6097
DOI10.11392/jsao1972.14.971

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Abstract Vascular grafts were implanted in the abdominal aorta of 39 adult mongrel dogs (14.07±3.24kg) using synthetic absorbable suture materials, that is polygiycolic acid (PGA) and polydioxanon (PDS), and nonabsorbable polypropylene (PP) as a control. The macroscopic findings and the histologic examination showed that the anastomotic sites using absorbable suture materials have healed better marphologicaily than that using PP. There was no evidence of suture line disruptions or aneurysm formation and any deffernces between PGA and PP in tensil strengh and bursting pressure were not observed at 12 months after implantation. The autnors concluded that syntheic absorbable suture materials such as PGA, PDS are safty and useful in small vascular anastomosis. 血管吻合治療に対して縫合糸がどのように関与し影響を与えているのかを、吸収性ならびに非吸収性縫合糸を用いて基礎的に検討し、吸収性縫合糸の血管吻合への応用の得失について明らかにした。雑犬39頭の腹部大動脈に代用血管を吸収性Polyglycolic Acid(PGA)糸, Polydloxanon (PDS)糸, contrlとして非吸収性のPolypropylene (PP)糸を用いて移植した。PGA糸吻合部は縫合糸が吸収された後では異物反応は消失し、長期になる程良好な組織治癒を示した。PP糸側は硝子化結合織が存在し、吻合形状の平滑化を妨げていた。全例に吻合不全、動脈瘤の発生をみず、12ヵ月後の引つ張り及び耐圧試験ではPGA側とPP側の間に有意差を認めなかつた。縫合糸の吻合部強度への関与は長期になる程少なくなる事が確認された。PDS糸はmonofilament構造の吸収性縫合糸であり、抗血栓性に優れ組織損傷が少なく、小口径血管吻合ではより理想に近い糸であると考えられた。
AbstractList Vascular grafts were implanted in the abdominal aorta of 39 adult mongrel dogs (14.07±3.24kg) using synthetic absorbable suture materials, that is polygiycolic acid (PGA) and polydioxanon (PDS), and nonabsorbable polypropylene (PP) as a control. The macroscopic findings and the histologic examination showed that the anastomotic sites using absorbable suture materials have healed better marphologicaily than that using PP. There was no evidence of suture line disruptions or aneurysm formation and any deffernces between PGA and PP in tensil strengh and bursting pressure were not observed at 12 months after implantation. The autnors concluded that syntheic absorbable suture materials such as PGA, PDS are safty and useful in small vascular anastomosis. 血管吻合治療に対して縫合糸がどのように関与し影響を与えているのかを、吸収性ならびに非吸収性縫合糸を用いて基礎的に検討し、吸収性縫合糸の血管吻合への応用の得失について明らかにした。雑犬39頭の腹部大動脈に代用血管を吸収性Polyglycolic Acid(PGA)糸, Polydloxanon (PDS)糸, contrlとして非吸収性のPolypropylene (PP)糸を用いて移植した。PGA糸吻合部は縫合糸が吸収された後では異物反応は消失し、長期になる程良好な組織治癒を示した。PP糸側は硝子化結合織が存在し、吻合形状の平滑化を妨げていた。全例に吻合不全、動脈瘤の発生をみず、12ヵ月後の引つ張り及び耐圧試験ではPGA側とPP側の間に有意差を認めなかつた。縫合糸の吻合部強度への関与は長期になる程少なくなる事が確認された。PDS糸はmonofilament構造の吸収性縫合糸であり、抗血栓性に優れ組織損傷が少なく、小口径血管吻合ではより理想に近い糸であると考えられた。
Author SATO A.
INABA M.
NAKAYAMA K.
SAKAI H.
IZUMI U.
SANEJIMA N.
SASAJIMA T.
KOKUBO M.
KUBO Y.
MORIMOTO N.
Author_FL 和泉 裕一
中山 一雄
笹嶋 唯博
境 普子
森本 典雄
佐藤 綾子
久保 良彦
小窪 正樹
鮫島 夏樹
稲葉 雅史
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  fullname: 稲葉 雅史
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人工臓器
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人工臓器
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JAPANESE SOCIETY FOR ARTIFICIAL ORGANS
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Snippet Vascular grafts were implanted in the abdominal aorta of 39 adult mongrel dogs (14.07±3.24kg) using synthetic absorbable suture materials, that is polygiycolic...
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StartPage 971
SubjectTerms Absorbable suture materials
Polydioxanon
Polyglycolic Acid
vascular Anastomosis
Title The role of suture materials in small vascular anastomosis
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Volume 14
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