Perinatal human parvovirus B19 infection─6 fetuses of infected pregnant women

• Published in: Journal of Japan Society of Perinatal and Neonatal Medicine Vol. 56; no. 2; pp. 343 - 346
• Main Authors: Nagara, Syunsuke, Usui, Shinji, Ueda, Mako, Yasumi, Shunsuke, Yano, Ryuichiro, Terazawa, Daisuke, Kohno, Yoshinori, Yamagishi, Atsushi
• Format: Journal Article
• Language: Japanese
• Published: Japan Society of Perinatal and Neonatal Medicine 2020
• Subjects: cardiac failure; fetal hydrops; human parvovirus B19; intrauterine fetal death; twins
• ISSN: 1348-964X; 2435-4996
• DOI: 10.34456/jjspnm.56.2_343

We experienced 6 fetuses in pregnant women infected with PB19. There were 3 infected pregnant women in 2015 and 2 in 2019, and we found that the number of pregnant women infected with parvovirus B19 increased at the same time as the epidemic of parvovirus B19 infection. All of the infected pregnant women were raising their children, and infectious erythema was prevalent at the preschool children’s destination. Therefore, in order to prevent parvovirus B19 infection in pregnant women, wearing a mask and encouraging hand-washing should be emphasized at the screening of pregnant women. The outcomes of their fetuses included two cases of intrauterine fetal demise, one case of stillbirth due to abortion, and two cases of normal neonates, one case of heart failure. The severity of the symptoms ranged from severe to mild cases. Among severe cases, there was a case of term infant with anemia, heart failure, and persistent pulmonary hypertension of the newborn. In another case, of the dichorionic diamniotic twin, there were cases in which the first fetus died in utero and the second fetus died due to abortion due to Potter syndrome.