Follow up study of blood pressure and its correlated factors in the southern seaside community of Wakayama prefecture

• Published in: Journal of the Japanese Association for Cerebro-cardiovascular Disease Control Vol. 33; no. 1; pp. 19 - 24
• Main Authors: Hano Takuzo, Shiotani Masahiko, Baba Akira, Mizukoshi Masato, Kasamatsu Ken, Hashizumel Toshikazu, Imanishi Toshio, Arita Mikio, Taguchi Seiichiro, Nishio Ichiro
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Association for Cerebro-cardiovascular Disease Control 1998; 社団法人 日本循環器管理研究協議会
• Subjects: blood pressure change; body weight; hypertension; serum creatinine; total cholesterol; 体重; 総コレステロール; 血圧変化; 血清クレアチニン; 高血圧
• ISSN: 0914-7284
• DOI: 10.11381/jjcdp1974.33.19

We followed 187 residents of Kushimoto-cho Ohshima in the southern part of Wakayama prefec-ture for 20 years starting in 1975 in order to determine the changes in blood pressure over the 20 years and its correlated factors. Systolic and diastolic blood pressure (from 124.5/74.1mmHg to 147.2/84.2 mmHg), total cholesterol (from 211.4 to 224.6mg/dl) and blood glucose levels (from 71.5 to 100. 7mg/ dl) were increased but body weight and plasma creatinine level did not. Fifty five percent of those subjects initially with normal blood pressure shifted to borderline hypertension or definite hypertension and 44.9 percents remained in the normal range. Systolic blood pressure in 1975 was significantly correlated with age (p<0.01), body weight (P = 0.06), and plasma glucose level (p=0.023) in multi-regression analysis. Diastolic blood pressure was significantly correlated with body weight (0.002) and total cholesterol level (p =0.043). Plasma creatinine level and its increase during 20 years were significant correlated factors for the increase of diastolic blood pressure (p <0.001). Increase of total cholesterol level was significant correlated with the increase of blood pressure in females (p <0.001) but not in males. 和歌山県の南端の串本町大島で血圧およびその関連因子の20年間の変化およびその関連を調査した。20年の経過で収縮期血圧, 拡張期血圧, 総コレステロール値, 血糖値は上昇傾向を示したが, 体重, 血清クレアチニン値は変化しなかった。正常血圧者の55.1%が境界域高血圧あるいは高血圧の領域となった。収縮期血圧値には年齢, 体重, 血糖値が有意な説明変数であり, 収縮期血圧の上昇には血清クレアチニンおよびその増加が有意な説明変数であった。拡張期血圧については体重, 弱いながら総コレステロールが有意な説明変数となり, 拡張期血圧の上昇には血清クレアチニンおよびその増加が有意な因子であった。女性における血圧の上昇には総コレステロールの上昇が有意な因子であったが、男性ではその関与は低かった。