The study to implement cancer genomic medical system for pediatric cancer predispositions Pediatric Hereditary Tumor Study Group (PAHTY) / Panel of Li-Fraumeni Syndrome, The Japanese Society for Familial Tumor

• Published in: JOURNAL OF FAMILIAL TUMORS Vol. 19; no. 1; pp. 19 - 23
• Main Author: Kumamoto, Tadashi
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Society for Familial Tumors 2019; 一般社団法人日本遺伝性腫瘍学会; The Japanese Society for Hereditary Tumors
• Subjects: Pediatric Cancer Predispositions, Li-Fraumeni syndrome, Guideline, Genetic counseling; 小児遺伝性腫瘍，リー・フラウメニ症候群，ガイドライン，遺伝カウンセリング
• ISSN: 1346-1052; 2189-6674
• DOI: 10.18976/jsft.19.1_19

Our study group consists of more than 40 participants / collaborators including experts in pediatric oncology, cancer predisposition, and guideline preparation, genetic counselor, ethicologists, epidemiologists, and member of the Children’s Cancer Association of Japan. The object is to construct medical system based on precision genetics for patients with pediatric cancer predispositions, and the tasks are to prepare guidelines on medical care and genetic counselling for pediatric cancer predispositions, especially Li-Fraumeni syndrome. Guidelines of medical care and genetic counselling will be developed based on detailed evidences obtained by systematic review of relevant literatures. Furthermore, we will publish summaries of the recommended surveillance systems for pediatric cancer predispositions, which was formulated in the Childhood Cancer Predispositon Workshop of the American Association for Cancer Research in 2016 and published in the journal Clinical Cancer Research in 2017.