An Efficient Approach to Quinolines via Friedländer Synthesis Catalyzed by Cuprous Triflate

A mild and efficient route for the synthesis of quinolines utilizing cuprous triflate (Cu(OTf)2) as a novel catalyst via Friedländer annulation in excellent yields at room temperature under solvent-free conditions was described.

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Bibliographic Details
Published inChemical & Pharmaceutical Bulletin Vol. 58; no. 2; pp. 212 - 213
Main Authors Soleimani, Ebrahim, Khodaei, Mohammad Mehdi, Batooie, Nasim, Samadi, Saadi
Format Journal Article
LanguageEnglish
Japanese
Published TOKYO The Pharmaceutical Society of Japan 01.02.2010
Pharmaceutical Society of Japan
Pharmaceutical Soc Japan
Japan Science and Technology Agency
Subjects
Catalysis
Chemistry
Chemistry, Medicinal
Chemistry, Multidisciplinary
cuprous triflate
Friedländer synthesis
Life Sciences & Biomedicine
Mesylates - chemistry
Molecular Structure
Pharmacology & Pharmacy
Physical Sciences
quinoline
Quinolines - chemical synthesis
Quinolines - chemistry
Science & Technology
solvent-free
Temperature
Friedlander synthesis
MILD
FUNCTIONALIZED QUINOLINES
ACID
O-AMINOARYL KETONES
ONE-STEP SYNTHESIS
ANNULATION
ANILINES
PROTOCOL
quinoline
solvent-free
cuprous triflate
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Summary:A mild and efficient route for the synthesis of quinolines utilizing cuprous triflate (Cu(OTf)2) as a novel catalyst via Friedländer annulation in excellent yields at room temperature under solvent-free conditions was described.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.58.212