Age-related character of glomerular lesions in IgA nephritis. (2) Histopathological peculiarity in childhood onset

Histopathological analysis was performed in the first renal biopsy specimens of patients over and under 10 yrs of IgA nephritis. They were divided clinically into two groups, the one with remission and the other with prolonged disease state respectively. Increased mesangial sclerosis, frequent occur...

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Published inNihon Jinzo Gakkai shi Vol. 34; no. 1; pp. 33 - 39
Main Authors SHIGEMATSU, HIDEKAZU, ITO, NOBUO, ISHIGAME, HIROKI, EHARA, TAKASHI, KATO, MASAHIRO, WASHIZAWA, KAZUHIKO, NARAMOTO, ATSUHIKO, NAKAZAWA, KOU, YAMAGUCHI, NAOTO, DUAN, HUI-JUN, TAKAMI, HIROYA, KASAHARA, HIROSHI
Format Journal Article
LanguageEnglish
Published Japan Japanese Society of Nephrology 1992
Subjects
Adolescent
Age Factors
Biopsy
Child
Female
Glomerulonephritis, IGA - pathology
Humans
IgA nephritis, childhood, mesangial sclerosis, segmental lesions, carry-over
Kidney Glomerulus - pathology
Kidney Glomerulus - ultrastructure
Male
Microscopy, Electron
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Summary:Histopathological analysis was performed in the first renal biopsy specimens of patients over and under 10 yrs of IgA nephritis. They were divided clinically into two groups, the one with remission and the other with prolonged disease state respectively. Increased mesangial sclerosis, frequent occurrence of segmental glomerular lesions and tubulointerstitial change were significantly evident in the group with prolonged disease state. It is suggested that similar glomerular events are progressing in IgA nephritis which is carried over to adult age.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0385-2385
1884-0728
DOI:10.14842/jpnjnephrol1959.34.33