The role of inflammation in cervical cancer

• Published in: Advances in experimental medicine and biology Vol. 816; p. 377
• Main Authors: Deivendran, S, Marzook, K Hezlin, Radhakrishna Pillai, M
• Format: Journal Article
• Language: English
• Published: United States 01.01.2014
• Subjects: Animals; Cell Transformation, Neoplastic - genetics; Cell Transformation, Neoplastic - immunology; Female; Humans; Inflammation - complications; Inflammation - epidemiology; Inflammation - therapy; Inflammation - virology; Inflammation Mediators - physiology; Papillomavirus Infections - complications; Papillomavirus Infections - epidemiology; Papillomavirus Infections - therapy; Uterine Cervical Neoplasms - epidemiology; Uterine Cervical Neoplasms - etiology; Uterine Cervical Neoplasms - pathology; Uterine Cervical Neoplasms - therapy

Knowledge regarding cervical cancer and human papillomavirus is expanding rapidly. Inflammation subsequent to viral infection is a driving force that accelerates cancer development. The infiltrated immune cells and their secretory cytokines along with chemokines and growth factors greatly contribute...