The role of inflammation in cervical cancer

Knowledge regarding cervical cancer and human papillomavirus is expanding rapidly. Inflammation subsequent to viral infection is a driving force that accelerates cancer development. The infiltrated immune cells and their secretory cytokines along with chemokines and growth factors greatly contribute...

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Bibliographic Details
Published inAdvances in experimental medicine and biology Vol. 816; p. 377
Main Authors Deivendran, S, Marzook, K Hezlin, Radhakrishna Pillai, M
Format Journal Article
LanguageEnglish
Published United States 01.01.2014
Subjects
Animals
Cell Transformation, Neoplastic - genetics
Cell Transformation, Neoplastic - immunology
Female
Humans
Inflammation - complications
Inflammation - epidemiology
Inflammation - therapy
Inflammation - virology
Inflammation Mediators - physiology
Papillomavirus Infections - complications
Papillomavirus Infections - epidemiology
Papillomavirus Infections - therapy
Uterine Cervical Neoplasms - epidemiology
Uterine Cervical Neoplasms - etiology
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - therapy
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Summary:Knowledge regarding cervical cancer and human papillomavirus is expanding rapidly. Inflammation subsequent to viral infection is a driving force that accelerates cancer development. The infiltrated immune cells and their secretory cytokines along with chemokines and growth factors greatly contribute the malignant traits of cervical cancer. A better understanding of the mechanisms related to inflammation and cancer progression in terms of pathogen survival, cancer development, progression, and metastasis will lead to innovative approach for treating cancer.
ISSN:0065-2598
DOI:10.1007/978-3-0348-0837-8_15