The Effect of Landiolol on Prevention for Supraventricular Arrhythmia after Thoracic Surgery

• Published in: CIRCULATION CONTROL Vol. 31; no. 1; pp. 36 - 38
• Main Authors: Shikada, Yasunori, Saitoh, Genkichi, Uno, Takahiro, Oishi, Kazushige, Kawabe, Satoshi, Koga, Satoko, Etoh, Takashi, Kaneko, Satoshi
• Format: Journal Article
• Language: English; Japanese
• Published: Japan Society of Circulation Control in Medicine 2010
• Subjects: arrhythmia; chest surgery; Landiolol
• ISSN: 0389-1844
• DOI: 10.11312/ccm.31.36

Tachyarrhythmia including atrial fibrillation is a major complication in respiratory surgery. In this study, we investigated the preventive effect of landiolol hydrochloride on atrial fibrillation and tachyarrhythmia in 50 patients who underwent pulmonary resection for lung cancer between June 2008 and October 2009. The patients included 33 males and 17 females and had a mean age of 70.3±8.6 years. Continuous administration of landiolol at 5μg/kg/min for 48 hours was initiated immediately after induction of anesthesia. Heart rate was monitored during and after surgery for detection of arrhythmia. No atrial fibrillation or tachyarrhythmia occurred in any patients. Our results suggest that intraoperative initiation of landiolol may prevent postoperative atrial fibrillation and tachyarrhythmia, which are common complications following pulmonary resection.