The effects of changing from isoflurane to desflurane on the recovery profile during the latter part of anesthesia

It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery. We therefore evaluated the effects of changing isoflurane to desflurane on emergence and recovery. Eighty-two patients were randomly assigned to rec...

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Published inActa medica Okayama Vol. 64; no. 5; pp. 307 - 316
Main Authors Kang, Hyun, Cha, Su-Man, Park, Sun-Gyoo, Jung, Yong-Hun, Woo, Young-Cheol, Kim, Jin-Yun, Koo, Gill-Hoi, Kim, Seong-Deok, Baek, Chong-Wha
Format Journal Article
LanguageEnglish
Published Japan 01.10.2010
Subjects
Adolescent
Adult
Aged
Anesthesia Recovery Period
Anesthetics, Inhalation
Female
Humans
Isoflurane - administration & dosage
Isoflurane - analogs & derivatives
Laparotomy - methods
Male
Middle Aged
Time Factors
Young Adult
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Summary:It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery. We therefore evaluated the effects of changing isoflurane to desflurane on emergence and recovery. Eighty-two patients were randomly assigned to receive isoflurane (Group I) or desflurane (Group D) or to change from isoflurane to desflurane anesthesia (Group X). At the point when there was an hour until the operation would end, isoflurane was replaced with 1 MAC of desflurane in Group X, and isoflurane and desflurane were maintained at 1 MAC in Groups I and D. When the operation ended, we compared the emergence and recovery characteristics among the 3 groups. Compared with Group I, Group X showed faster emergence and recovery. Group X and Group D showed similar emergence and recovery. In conclusion, changing isoflurane to desflurane during the latter part of anesthesia improves emergence and recovery.
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ISSN:0386-300X