重症腹部外傷の予後と血液型との関連
外傷においてO型は失血死のリスクが高いと報告があるが，一方で関連はないという報告もある。今回，緊急輸血を要する腹部外傷の予後と血液型が関連しているのかという点について検討した。【対象と方法】2008年から2020年に当センターに搬送された外傷症例を対象に後ろ向きに検討した。24時間以内にred blood cellを1単位以上輸血された腹部AIS3以上の外傷症例をO型と非O型で生存率，輸血量を検討した。【結果】対象は253例。平均年齢62歳，男性177例，女性76例，鈍的外傷93％，ISS 32。24時間後死亡率はO型12％，非O型13％，輸血量も12単位と9単位で有意差はなかった。頭部・胸部...
Saved in:
| Published in | 日本腹部救急医学会雑誌 Vol. 43; no. 7; pp. 1019 - 1026 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本腹部救急医学会
30.11.2023
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1340-2242 1882-4781 |
| DOI | 10.11231/jaem.43.1019 |
Cover
Loading…
| Abstract | 外傷においてO型は失血死のリスクが高いと報告があるが，一方で関連はないという報告もある。今回，緊急輸血を要する腹部外傷の予後と血液型が関連しているのかという点について検討した。【対象と方法】2008年から2020年に当センターに搬送された外傷症例を対象に後ろ向きに検討した。24時間以内にred blood cellを1単位以上輸血された腹部AIS3以上の外傷症例をO型と非O型で生存率，輸血量を検討した。【結果】対象は253例。平均年齢62歳，男性177例，女性76例，鈍的外傷93％，ISS 32。24時間後死亡率はO型12％，非O型13％，輸血量も12単位と9単位で有意差はなかった。頭部・胸部外傷が死因となったものを除外した検討でも死亡率に差はなく，多変量解析でもO型であることは死亡率と関連はなかった。【結語】輸血を要する腹部外傷においてO型は輸血量，予後に関連は認めなかった。 |
|---|---|
| AbstractList | 外傷においてO型は失血死のリスクが高いと報告があるが，一方で関連はないという報告もある。今回，緊急輸血を要する腹部外傷の予後と血液型が関連しているのかという点について検討した。【対象と方法】2008年から2020年に当センターに搬送された外傷症例を対象に後ろ向きに検討した。24時間以内にred blood cellを1単位以上輸血された腹部AIS3以上の外傷症例をO型と非O型で生存率，輸血量を検討した。【結果】対象は253例。平均年齢62歳，男性177例，女性76例，鈍的外傷93％，ISS 32。24時間後死亡率はO型12％，非O型13％，輸血量も12単位と9単位で有意差はなかった。頭部・胸部外傷が死因となったものを除外した検討でも死亡率に差はなく，多変量解析でもO型であることは死亡率と関連はなかった。【結語】輸血を要する腹部外傷においてO型は輸血量，予後に関連は認めなかった。 |
| Author | 岩瀬, 史明 萩原, 一樹 保坂, 啓太 |
| Author_xml | – sequence: 1 fullname: 岩瀬, 史明 organization: 山梨県立中央病院高度救命救急センター – sequence: 1 fullname: 萩原, 一樹 organization: 山梨県立中央病院高度救命救急センター – sequence: 1 fullname: 保坂, 啓太 organization: 山梨県立中央病院高度救命救急センター |
| BookMark | eNo9jz1LA0EYhBeJYIwp_Rl37ru7d7tXiQS_IGCj9bGbe1dzJFHu0tglikSItrET_ChSWVgoWvhn4mnuX3iHYjPzMAMDs0wqveMeErIK1AVgHNZijV1XcBcoBAukCkoxR0gFlYK5oA5jgi2Repq2DaXgeRSEqhKej66_b0bzi7f8fJo9TrKz19nw6fP9Mvu4mg2n87vB18tzdjsuuMjzyX0-eFghi1Z3Uqz_eY0cbG3uN3ac5t72bmOj6cRMMuoEgTSB8JSNPPR9gyKiHNFwqY0xSlgWBJHyjaWAkgJYQT1pIx5JH5WPSHmNrP_uxmlfH2J4krS7OjkNddJvtzoYlo9DwUNZSnn7v2kd6aSo-Q9WCWSh |
| ContentType | Journal Article |
| Copyright | 日本腹部救急医学会 |
| Copyright_xml | – notice: 日本腹部救急医学会 |
| DOI | 10.11231/jaem.43.1019 |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1882-4781 |
| EndPage | 1026 |
| ExternalDocumentID | article_jaem_43_7_43_1019_article_char_ja |
| GroupedDBID | ALMA_UNASSIGNED_HOLDINGS JSP KQ8 RJT |
| ID | FETCH-LOGICAL-j2720-997b9458fd5e66be4d03eeb37abbb84f299d86bf01e7011f4057fd3d76e86ee03 |
| ISSN | 1340-2242 |
| IngestDate | Wed Sep 03 06:31:01 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 7 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j2720-997b9458fd5e66be4d03eeb37abbb84f299d86bf01e7011f4057fd3d76e86ee03 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/jaem/43/7/43_1019/_article/-char/ja |
| PageCount | 8 |
| ParticipantIDs | jstage_primary_article_jaem_43_7_43_1019_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 2023/11/30 |
| PublicationDateYYYYMMDD | 2023-11-30 |
| PublicationDate_xml | – month: 11 year: 2023 text: 2023/11/30 day: 30 |
| PublicationDecade | 2020 |
| PublicationTitle | 日本腹部救急医学会雑誌 |
| PublicationTitleAlternate | 日腹部救急医会誌 |
| PublicationYear | 2023 |
| Publisher | 日本腹部救急医学会 |
| Publisher_xml | – name: 日本腹部救急医学会 |
| References | 19) Holcomb JB, Tilley BC, Baraniuk S, et al: Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA 2015; 313: 471-482. 18) Tutunjian AM, Arabian SS, Paolino J, et al: ABO blood groups do not predict progression of traumatic intracranial hemorrhage. J Clin Neurosci 2021; 90: 345-350. 24) Shima M, Fujimura Y, Nishiyama T, et al: ABO blood group genotype and plasma von Willebrand factor in normal individuals. Vox Sang 1995; 68: 236-240. 22) Gill JC, Endres-Brooks J, Bauer PJ, et al: The effect of ABO blood group on the diagnosis of von Willebrand disease. Blood 1987; 69: 1691-1695. 7) Chauleur C, Cochery-Nouvellon E, Mercier E, et al: Some hemostasis variables at the end of the population distributions are risk factors for severe postpartum hemorrhages. J Thromb Haemost 2008; 6: 2067-2074. 11) Miller JL, Harper H, McCarty HJ, et al: Time to hemostasis after trauma and transfusion by patient blood type. AACN Adv Crit Care 2022; 33: 154-161. 20) Kang JG, Ahn HJ, Kim GS, et al: The hemostatic profiles of patients with Type O and non-O blood after acute normovolemic hemodilution with 6% hydroxyethyl starch (130/0.4). Anesth Analg 2006; 103: 1543-1548. 1) Anstee DJ: The relationship between blood groups and disease. Blood 2010; 115: 4635-4643. 15) Schack A, Oreskov JO, Ekeloef S, et al: The impact of blood type on transfusion after major emergency abdominal surgery. Transfusion 2019; 59: 125-133. 10) Sauder MW, Wolff TW, LaRiccia AK, et al: The association of ABO blood groups and trauma outcomes: a retrospective analysis of 3779 patients. Int J Crit Illn Inj Sci 2021; 11: 73-78. 14) Mazzeffi M, Gupta R, Lonergan T, et al: ABO type and bleeding during adult ECMO. Intensive Care Med 2017; 43: 275-276. 3) Bruun-Rasmussen P, Dziegiel MH, Banasik K, et al: Associations of ABO and Rhesus D blood groups with phenome-wide disease incidence: a 41-year retrospective cohort study of 482,914 patients. Elife 2023; 12: e83116. 4) Kander T, Bjurström MF, Frigyesi A, et al: ABO and RhD blood group are not associated with mortality and morbidity in critically ill patients; a multicentre observational study of 29512 patients. BMC Anesthesiol 2022; 22: 91. 13) Hamsen U, Nohl A, Baumann A, et al: The influence of ABO blood group on mortality in major trauma. Orthop Rev (Pavia) 2019; 11: 8214. 21) Choi SJ, Ahn HJ, Lee JI: Comparison of coagulation factors and blood loss between O and non-O blood types following hydroxyethyl starch infusion. Korean J Anesthesiol 2010; 58: 344-350. 6) Bayan K, Tüzün Y, Yilmaz S, et al: Clarifying the relationship between ABO/Rhesus blood group antigens and upper gastrointestinal bleeding. Dig Dis Sci 2009; 54: 1029-1034. 2) Dentali F, Sironi AP, Ageno W, et al: ABO blood group and vascular disease: an update. Semin Thromb Hemost 2014; 40: 49-59. 5) Dentali F, Sironi AP, Ageno W, et al: Relationship between ABO blood group and hemorrhage: a systematic literature review and meta-analysis. Semin Thromb Hemost 2013; 39: 72-82. 25) Morelli VM, de Visser MC, van Tilburg NH, et al: ABO blood group genotypes, plasma von Willebrand factor levels and loading of von Willebrand factor with A and B antigens. Thromb Haemost 2007; 97: 534-541. 12) DeBot M, Eitel AP, Moore EE, et al: Blood type O is a risk factor for hyperfibrinolysis and massive transfusion after severe injury. Shock 2022; 58: 492-497. 8) Griffin RL, Jansen JO, Bosarge PL, et al: The association between ABO blood type and mortality among severity injured trauma patients. Shock 2020; 54: 205-208. 23) Gallinaro L, Cattini MG, Sztukowska M, et al: A shorter von Willebrand factor survival in O blood group subjects explains how ABO determinants influence plasma von Willebrand factor. Blood 2008; 111: 3540-3545. 16) Archer NM, Forbes PW, Dargie J, et al: Association of blood type with postsurgical mucosal bleeding in pediatric patients undergoing tonsillectomy with or without adenoidectomy. JAMA Netw Open 2020; 3: e201804. 17) Takayama W, Endo A, Koguchi H, et al: The impact of blood type O on mortality of severe trauma patients: a retrospective observational study. Crit Care 2018; 22: 100. 9) Takayama W, Endo A, Murata K, et al: The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study. Sci Rep 2021; 11: 16147. |
| References_xml | – reference: 6) Bayan K, Tüzün Y, Yilmaz S, et al: Clarifying the relationship between ABO/Rhesus blood group antigens and upper gastrointestinal bleeding. Dig Dis Sci 2009; 54: 1029-1034. – reference: 3) Bruun-Rasmussen P, Dziegiel MH, Banasik K, et al: Associations of ABO and Rhesus D blood groups with phenome-wide disease incidence: a 41-year retrospective cohort study of 482,914 patients. Elife 2023; 12: e83116. – reference: 16) Archer NM, Forbes PW, Dargie J, et al: Association of blood type with postsurgical mucosal bleeding in pediatric patients undergoing tonsillectomy with or without adenoidectomy. JAMA Netw Open 2020; 3: e201804. – reference: 12) DeBot M, Eitel AP, Moore EE, et al: Blood type O is a risk factor for hyperfibrinolysis and massive transfusion after severe injury. Shock 2022; 58: 492-497. – reference: 24) Shima M, Fujimura Y, Nishiyama T, et al: ABO blood group genotype and plasma von Willebrand factor in normal individuals. Vox Sang 1995; 68: 236-240. – reference: 1) Anstee DJ: The relationship between blood groups and disease. Blood 2010; 115: 4635-4643. – reference: 2) Dentali F, Sironi AP, Ageno W, et al: ABO blood group and vascular disease: an update. Semin Thromb Hemost 2014; 40: 49-59. – reference: 20) Kang JG, Ahn HJ, Kim GS, et al: The hemostatic profiles of patients with Type O and non-O blood after acute normovolemic hemodilution with 6% hydroxyethyl starch (130/0.4). Anesth Analg 2006; 103: 1543-1548. – reference: 22) Gill JC, Endres-Brooks J, Bauer PJ, et al: The effect of ABO blood group on the diagnosis of von Willebrand disease. Blood 1987; 69: 1691-1695. – reference: 5) Dentali F, Sironi AP, Ageno W, et al: Relationship between ABO blood group and hemorrhage: a systematic literature review and meta-analysis. Semin Thromb Hemost 2013; 39: 72-82. – reference: 7) Chauleur C, Cochery-Nouvellon E, Mercier E, et al: Some hemostasis variables at the end of the population distributions are risk factors for severe postpartum hemorrhages. J Thromb Haemost 2008; 6: 2067-2074. – reference: 21) Choi SJ, Ahn HJ, Lee JI: Comparison of coagulation factors and blood loss between O and non-O blood types following hydroxyethyl starch infusion. Korean J Anesthesiol 2010; 58: 344-350. – reference: 23) Gallinaro L, Cattini MG, Sztukowska M, et al: A shorter von Willebrand factor survival in O blood group subjects explains how ABO determinants influence plasma von Willebrand factor. Blood 2008; 111: 3540-3545. – reference: 14) Mazzeffi M, Gupta R, Lonergan T, et al: ABO type and bleeding during adult ECMO. Intensive Care Med 2017; 43: 275-276. – reference: 11) Miller JL, Harper H, McCarty HJ, et al: Time to hemostasis after trauma and transfusion by patient blood type. AACN Adv Crit Care 2022; 33: 154-161. – reference: 25) Morelli VM, de Visser MC, van Tilburg NH, et al: ABO blood group genotypes, plasma von Willebrand factor levels and loading of von Willebrand factor with A and B antigens. Thromb Haemost 2007; 97: 534-541. – reference: 13) Hamsen U, Nohl A, Baumann A, et al: The influence of ABO blood group on mortality in major trauma. Orthop Rev (Pavia) 2019; 11: 8214. – reference: 15) Schack A, Oreskov JO, Ekeloef S, et al: The impact of blood type on transfusion after major emergency abdominal surgery. Transfusion 2019; 59: 125-133. – reference: 10) Sauder MW, Wolff TW, LaRiccia AK, et al: The association of ABO blood groups and trauma outcomes: a retrospective analysis of 3779 patients. Int J Crit Illn Inj Sci 2021; 11: 73-78. – reference: 9) Takayama W, Endo A, Murata K, et al: The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study. Sci Rep 2021; 11: 16147. – reference: 17) Takayama W, Endo A, Koguchi H, et al: The impact of blood type O on mortality of severe trauma patients: a retrospective observational study. Crit Care 2018; 22: 100. – reference: 4) Kander T, Bjurström MF, Frigyesi A, et al: ABO and RhD blood group are not associated with mortality and morbidity in critically ill patients; a multicentre observational study of 29512 patients. BMC Anesthesiol 2022; 22: 91. – reference: 8) Griffin RL, Jansen JO, Bosarge PL, et al: The association between ABO blood type and mortality among severity injured trauma patients. Shock 2020; 54: 205-208. – reference: 18) Tutunjian AM, Arabian SS, Paolino J, et al: ABO blood groups do not predict progression of traumatic intracranial hemorrhage. J Clin Neurosci 2021; 90: 345-350. – reference: 19) Holcomb JB, Tilley BC, Baraniuk S, et al: Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA 2015; 313: 471-482. |
| SSID | ssib001550148 ssib039893137 ssib058493785 ssib002484627 ssj0061899 |
| Score | 2.3374288 |
| Snippet | 外傷においてO型は失血死のリスクが高いと報告があるが，一方で関連はないという報告もある。今回，緊急輸血を要する腹部外傷の予後と血液型が関連しているのかという点について検討した。【対象と方法】2008年から2020年に当センターに搬送された外傷症例を対象に後ろ向きに検討した。24時間以内にred blood... |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 1019 |
| SubjectTerms | フォンビルブラント因子 血液型 輸血 重症外傷 |
| Title | 重症腹部外傷の予後と血液型との関連 |
| URI | https://www.jstage.jst.go.jp/article/jaem/43/7/43_1019/_article/-char/ja |
| Volume | 43 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本腹部救急医学会雑誌, 2023/11/30, Vol.43(7), pp.1019-1026 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NaxQxFA9tBfEifuI3PfiOs85MMjPJMTM7S1EqCC30tmxmMoeCtUh78dQqUkG9Vk-CH4eePHhQ9OA_U1e7_4XvZWZ3p9BDLcISQvKbl5e8zOT3svlg7HaQDExVhoVnsMd4wkjfk3xQeDTDXxT4him3F2bxfrywLO6uRCszs29bq5Y2N0yneHLkvpKTWBXT0K60S_YfLDsRigkYR_tiiBbG8Fg2hlwBOvOyC3kCKqF4LkFGkCqXxUFLyCPQAlRMERlCihiO_BF0DrmAVIN0mDQHmY2zJMnRAS2DyGNI8RcSRiEmbWEmchTJ16Er1AfN25SXJKBuOnKRDHR2lJKYhfIDipCEyGmbQZo6_bugY6dtBkq74lIHRiVR_8lEr6tHCFpRe5CYjHqQE9VzVcBSsOh8ipegfIdHSA6qV-OxINnUHXVL1RSPOT1QXdcYXWrORj4pz5um1ro9lRLy8RGOTef_7-3RGle48D1kS_XAY-s0cm5op297MKrPrGpeuqQ1suCnU7VYCvLC-OgREAm7u3rBPuwI3pk-duhQ8abL9gnWF7yfUEDY_jiHNv1h9iw7FaIDRneD3Htw6P9Vv-1IhwJ5bDghslwhDQ6mxBdZLtLgqWMaB9Ld7DpplvHpt6j8nbbqyAtX0Usar7B0pG_pHDvbeGvzutb2PJtZHVxgpxeb9SgXGR_tvP7zZufg-ffRs73hp93h02_7259__Xgx_Plqf3vv4P3W769fhu9eYhzTR7sfRlsfL7HlXr6ULXjNNSTeKi1S8JRKjBKRrMrIxrGxovS5tYbjV84YKSokdKWMTeUHNsHRsiIXqCp5mcRWxtb6_DKbW3u0Zq-weeuLMgmtLYxBV4oLVQSVDfyq4saWZaiuMllXt79enzXTP7ahrp380evszPRtuMHmNh5v2ptItTfMLWf1v48MpGs |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E9%87%8D%E7%97%87%E8%85%B9%E9%83%A8%E5%A4%96%E5%82%B7%E3%81%AE%E4%BA%88%E5%BE%8C%E3%81%A8%E8%A1%80%E6%B6%B2%E5%9E%8B%E3%81%A8%E3%81%AE%E9%96%A2%E9%80%A3&rft.jtitle=%E6%97%A5%E6%9C%AC%E8%85%B9%E9%83%A8%E6%95%91%E6%80%A5%E5%8C%BB%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E5%B2%A9%E7%80%AC%2C+%E5%8F%B2%E6%98%8E&rft.au=%E8%90%A9%E5%8E%9F%2C+%E4%B8%80%E6%A8%B9&rft.au=%E4%BF%9D%E5%9D%82%2C+%E5%95%93%E5%A4%AA&rft.date=2023-11-30&rft.pub=%E6%97%A5%E6%9C%AC%E8%85%B9%E9%83%A8%E6%95%91%E6%80%A5%E5%8C%BB%E5%AD%A6%E4%BC%9A&rft.issn=1340-2242&rft.eissn=1882-4781&rft.volume=43&rft.issue=7&rft.spage=1019&rft.epage=1026&rft_id=info:doi/10.11231%2Fjaem.43.1019&rft.externalDocID=article_jaem_43_7_43_1019_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1340-2242&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1340-2242&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1340-2242&client=summon |