腹腔鏡下肝切除術で診断した肝多発性壊死性結節の1例
肝孤立性壊死性結節はまれな肝内占居性病変であり,多発する可能性がある.今回,腹腔鏡下肝切除術を行い,肝多発性壊死性結節と診断した1例を経験したので報告する.症例は71歳の女性で,12年前に乳癌に対して乳房部分切除を施行され,無再発であった.経過観察目的のCTで肝両葉に最大径10mmの腫瘤を5個指摘された.腫瘤は超音波で境界明瞭な低エコー領域として描出され,PET-CTでFDG集積亢進を認めず,それぞれ同様の形態であった.経皮的肝生検では凝固壊死を認めるのみであり,確定診断には至らなかった.転移性肝癌との鑑別のため,腹腔鏡下肝部分切除・生検を施行し,肝孤立性壊死性結節と診断した.肝内多発病変はい...
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Published in | 日本臨床外科学会雑誌 Vol. 82; no. 3; pp. 616 - 622 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
日本臨床外科学会
2021
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Subjects | |
Online Access | Get full text |
ISSN | 1345-2843 1882-5133 |
DOI | 10.3919/jjsa.82.616 |
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Abstract | 肝孤立性壊死性結節はまれな肝内占居性病変であり,多発する可能性がある.今回,腹腔鏡下肝切除術を行い,肝多発性壊死性結節と診断した1例を経験したので報告する.症例は71歳の女性で,12年前に乳癌に対して乳房部分切除を施行され,無再発であった.経過観察目的のCTで肝両葉に最大径10mmの腫瘤を5個指摘された.腫瘤は超音波で境界明瞭な低エコー領域として描出され,PET-CTでFDG集積亢進を認めず,それぞれ同様の形態であった.経皮的肝生検では凝固壊死を認めるのみであり,確定診断には至らなかった.転移性肝癌との鑑別のため,腹腔鏡下肝部分切除・生検を施行し,肝孤立性壊死性結節と診断した.肝内多発病変はいずれも同様の形態であり,肝多発性壊死性結節と診断した.術後4カ月経過観察し,病変の増大は認めていない.肝孤立性壊死性結節の多発例は非常にまれであり,文献的考察を加えて報告する. |
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AbstractList | 肝孤立性壊死性結節はまれな肝内占居性病変であり,多発する可能性がある.今回,腹腔鏡下肝切除術を行い,肝多発性壊死性結節と診断した1例を経験したので報告する.症例は71歳の女性で,12年前に乳癌に対して乳房部分切除を施行され,無再発であった.経過観察目的のCTで肝両葉に最大径10mmの腫瘤を5個指摘された.腫瘤は超音波で境界明瞭な低エコー領域として描出され,PET-CTでFDG集積亢進を認めず,それぞれ同様の形態であった.経皮的肝生検では凝固壊死を認めるのみであり,確定診断には至らなかった.転移性肝癌との鑑別のため,腹腔鏡下肝部分切除・生検を施行し,肝孤立性壊死性結節と診断した.肝内多発病変はいずれも同様の形態であり,肝多発性壊死性結節と診断した.術後4カ月経過観察し,病変の増大は認めていない.肝孤立性壊死性結節の多発例は非常にまれであり,文献的考察を加えて報告する. |
Author | 大谷, 広美 河崎, 秀樹 渡邊, 常太 佐川, 庸 前田, 智治 坂本, 明優 |
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References_xml | – reference: 22) Koffron A, Geller D, Gamblin TC, et al : Laparoscopic liver surgery : Shifting the management of liver tumors. Hepatology 2006 ; 44 : 1694-1700 – reference: 2) Zhou YM, Li B, Xu F, et al : Clinical features of solitary necrotic nodule of the liver. Hepatobiliary Pancreat Dis Int 2008 ; 7 : 485-489 – reference: 19) Nguyen KT, Gamblin TC, Geller DA : World review of laparoscopic liver resection-2,804 patients. Ann Surg 2009 ; 250 : 831-841 – reference: 12) Wang HQ, Wu ZS, Li DW : Solitary necrotic nodule of the liver : a report of two cases and review of the literature. Case Reports Hepatol 2011 ; 2011 : 845406 – reference: 17) Hwang JY, Lee JE, Jung MJ : A Challenging Case of Solitary Necrotic Nodules of the Liver Mimicking Hepatic Metastases : CT, MRI, and PET-CT Findings. J Belg Soc Radiol 2020 ; 104 : 16 – reference: 7) Tsui WM, Yuen RW, Chow LT, et al : Solitary necrotic nodule of the liver : parasitic origin? J Clin Pathol 1992 ; 45 : 975-978 – reference: 11) Otani K, Chijiiwa K, Kondo K, et al : Enlarged solitary necrotic nodule of the liver misinterpreted as a metastatic liver cancer. Clin J Gastroenterol 2009 ; 2 : 355-360 – reference: 1) Geng L, Lin C, Huang B, et al : Solitary necrotic nodule of the liver : MR findings in 33 pathologically proved lesions. Eur J Radiol 2012 ; 81 : 623-629 – reference: 4) Shepherd NA, Lee G : Solitary necrotic nodules of the liver simulating hepatic metastases. J Clin Pathol 1983 ; 36 : 1181-1183 – reference: 3) Sundaresan M, Lyons B, Akosa AB : ‘Solitary’ necrotic nodules of the liver : an aetiology reaffirmed. Gut 1991 ; 32 : 1378-1380 – reference: 14) Imura S, Miyake K, Ikemoto T, et al : Rapid-growing solitary necrotic nodule of the liver. J Med Invest 2006 ; 53 : 325-329 – reference: 5) Colagrande S, Paolucci ML, Messerini L, et al : Solitary necrotic nodules of the liver : cross-sectional imaging findings and follow-up in nine patients. AJR Am J Roentgenol 2008 ; 191 : 1122-1128 – reference: 13) Yoon KH, Yun KJ, Lee JM, et al : Solitary necrotic nodules of the liver mimicking hepatic metastasis : report of two cases. Korean J Radiol 2000 ; 1 : 165-168 – reference: 18) Reich H, McGlynn F, DeCaprio J, et al : Laparoscopic excision of benign liver lesions. Obstet Gynecol 1991 ; 78 : 956-958 – reference: 8) Deniz K, Coban G : Solitary necrotic nodule of the liver : always benign? J Gastrointest Surg 2010 ; 14 : 536-540 – reference: 21) 中島隆善,塚本忠司,金沢景繁他:腹腔鏡下肝切除術を施行した肝細胞癌との鑑別が困難であった 大型再生結節(LRN)の1例.肝臓 2014;55:384-391 – reference: 16) Goel G, Rao S, Khurana N, et al : Solitary Necrotic Nodule of Liver (SNNL) : A Report of Two Cases. J Clin Diagn Res 2014 ; 8 : 115-116 – reference: 10) De Luca M, Luigi B, Formisano C, et al : Solitary necrotic nodule of the liver misinterpreted as malignant lesion : considerations on two cases. J Surg Oncol 2000 ; 74 : 219-222 – reference: 15) Kondi-Pafiti AI, Grapsa DS, Kairi-Vasilatou ED, et al : “Solitary” necrotic nodule of the liver : an enigmatic entity mimicking malignancy. Int J Gastrointest Cancer 2006 ; 37 : 74-78 – reference: 9) Asai K, Sumiyama Y, Watanabe M, et al : Multiple necrotic nodules of the liver simulating liver metastasis. J Hepatobiliary Pancreat Surg 2007 ; 14 : 414-420 – reference: 20) Tsinberg M, Tellioglu G, Simpfendorfer CH, et al : Comparison of laparoscopic versus open liver tumor resection : a case-controlled study. Surg Endosc 2009 ; 23 : 847-853 – reference: 6) Patti R, Cabibi D, Sparacello M, et al : Solitary necrotic nodule of the liver : different pathological findings express a different histogenesis. Case Rep Gastroenterol 2008 ; 2 : 149-154 |
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SubjectTerms | 多発 孤立性壊死性結節 腹腔鏡下肝切除 |
Title | 腹腔鏡下肝切除術で診断した肝多発性壊死性結節の1例 |
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