Angiostrongylus cantonensis Is an Important Cause of Eosinophilic Meningitis in Southern Vietnam

We utilized polymerase chain reaction (PCR) to demonstrate that Angiostrongylus cantonensis was responsible for 67.3% of 55 cases of eosinophilic meningitis from a cohort of 1,690 adult patients with CNS infection at a tertiary hospital in southern Vietnam. Longer duration of illness, depressed cons...

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Bibliographic Details
Published inClinical infectious diseases Vol. 64; no. 12; pp. 1784 - 1787
Main Authors McBride, Angela, Chau, Tran Thi Hong, Hong, Nguyen Thi Thu, Mai, Nguyen Thi Hoang, Anh, Nguyen To, Thanh, Tran Tan, Van, Tran Thi Hue, Xuan, Le Thi, Sieu, Tran Phu Manh, Thai, Le Hong, Van Chuong, Ly, Sinh, Dinh Xuan, Phong, Nguyen Duy, Phu, Nguyen Hoan, Day, Jeremy, Nghia, Ho Dang Trung, Hien, Tran Tinh, Van Vinh Chau, Nguyen, Thwaites, Guy, Van Tan, Le
Format Journal Article
LanguageEnglish
Published United States Oxford University Press 15.06.2017
Subjects
Adolescent
Adult
Angiostrongylus cantonensis - genetics
Angiostrongylus cantonensis - isolation & purification
Animals
BRIEF REPORT
Cohort Studies
Eosinophilia - epidemiology
Eosinophilia - parasitology
Female
Humans
Male
Meningitis - epidemiology
Meningitis - parasitology
Polymerase Chain Reaction
Prospective Studies
Strongylida Infections - diagnosis
Strongylida Infections - epidemiology
Strongylida Infections - parasitology
Tertiary Care Centers
Vietnam - epidemiology
Young Adult
Vietnam
Angiostrongylus cantonensis
eosinophilic meningitis
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Summary:We utilized polymerase chain reaction (PCR) to demonstrate that Angiostrongylus cantonensis was responsible for 67.3% of 55 cases of eosinophilic meningitis from a cohort of 1,690 adult patients with CNS infection at a tertiary hospital in southern Vietnam. Longer duration of illness, depressed consciousness, and peripheral blood eosinophilia were associated with PCR positivity.
Bibliography:Correspondence: A. McBride, Oxford University Clinical Research Unit, 764 Vo Van Kiet, Quan 5, Ho Chi Minh City, Vietnam (angelamcbride@doctors.net.uk).
aAlphabetically listed and contributed equally to the manuscript.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/cix118