InBr3-catalyzed alkynylation and allylation of acid chlorides: A facile synthesis of alkynyl and allyl ketones
Alkynylsilanes and allyltrimethylsilane undergo smooth coupling with acid chlorides in the presence of 5 mol% of indium tribromide under mild conditions to afford the corresponding alpha,beta-acetylenic ketones and beta,gamma-unsaturated ketones in excellent yields in a short reaction time with high...
Saved in:
Published in | Synthesis (Stuttgart) no. 15; pp. 2390 - 2394 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
STUTTGART
Thieme Medical Publishers
31.10.2003
|
Subjects | |
Online Access | Get more information |
Cover
Loading…
Summary: | Alkynylsilanes and allyltrimethylsilane undergo smooth coupling with acid chlorides in the presence of 5 mol% of indium tribromide under mild conditions to afford the corresponding alpha,beta-acetylenic ketones and beta,gamma-unsaturated ketones in excellent yields in a short reaction time with high selectivity. |
---|---|
ISSN: | 0039-7881 |
DOI: | 10.1055/s-2003-42438 |