Phase 1 clinical studies of oral garenoxacin in healthy Japanese adult subjects

• Published in: Japanese Journal of Chemotherapy Vol. 55; no. Supplement1; pp. 95 - 115
• Main Author: Uchida, Eiji
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of Chemotherapy 01.10.2007; 公益社団法人 日本化学療法学会
• Subjects: des-fluoro -quinolone; garenoxacin; pharmacokinetic; T-3811MEa
• ISSN: 1340-7007; 1884-5886
• DOI: 10.11250/chemotherapy1995.55.Supplement1_95

Pharmacokinetic profiles, safety, and food effect of oral garenoxacin mesilate hydrate (GRNX), a novel des-F (6)-quinolone, were evaluated in studies with healthy Japanese adult subjects. The intrinsic ethnic factor of GRNX was investigated by reviewing comparison of pharmacokinetic parameters by Ja...