CLINICAL STUDIES ON A NEW CEPHEM, CEFEPIME, IN RESPIRATORY TRACT INFECTION

• Published in: CHEMOTHERAPY Vol. 39; no. Supplement2; pp. 451 - 454
• Main Authors: Sato, Kei, Matsuura, Tatsuo, Inoue, Torao, Hirose, Takahito, Miyata, Masakazu
• Format: Journal Article
• Language: English; Japanese
• Published: Japanese Society of Chemotherapy 1991; 公益社団法人 日本化学療法学会
• Subjects: Cefepime (BMY-28142); 呼吸器感染症; 臨床的検討
• ISSN: 0009-3165; 1884-5894
• DOI: 10.11250/chemotherapy1953.39.Supplement2_451

Cefepime, a newly developed cephem, was given intravenously at a dose of 1 g every 12 hours for 3-15 days to 8 patients with respiratory tract infections including 3 cases of pneumonia, 1 case of lung abscess, 3 cases of acute exacerbation of chronic respiratory infection and 1 case of FUO (fever of unknown origin) Therapeutic response was excellent in 1, good in 2, fair in 1 and poor in 3 cases. Causative organisms were revealed in 2 cases: Serratia liquefaciens and Pseudomonas aeruginosa. No side effects or abnormal laboratory findings related to cefepime were observed.