Clinical study of cefozopran in obstetrics and gynecology

• Published in: CHEMOTHERAPY Vol. 41; no. Supplement4; pp. 675 - 678
• Main Authors: Yamato, Tatsuo, Hayashi, Moichiroh, Ishikawa, Takuji, Hayashi, Shigeoki, Tan, Hideto, Imagawa, Nobuyuki
• Format: Journal Article
• Language: English; Japanese
• Published: Japanese Society of Chemotherapy 1993; 公益社団法人 日本化学療法学会
• Subjects: CZOP; 臨床的検討
• ISSN: 0009-3165; 1884-5894
• DOI: 10.11250/chemotherapy1953.41.Supplement4_675

The efficacy and safety of cefozopran on infectious diseases in the obstetric and gynecological field were investigated in 6 patients who consisted of 2 with pelvic peritonitis, 2 with endometritis, 1 with Bartholin's abscess, and 1 with vaginal hematoma due to inflammatory vaginal atresia. The drug was intravenously infused at a dose of 1.0g twice a day. The drug was clinically effective in all patients. Causative bacteria were eliminated in all 5 patients in whom the bacteriological effect of the drug could be assessed. The above results suggest that the drug is useful for treatment of infectious diseases in the obstetric and gynecological field.