Clinical study of cefozopran

We evaluated the clinical efficacy and safety of cefozopran, a new cephem antibiotics. Cefozopran was administered to 2 with bacteremia, 9 with respiratory tract infection. The patients received the drug, intravenously, for 5 to 15 days in dose of 0.5-2.0 g/day. Clinical effects were excellent in 1,...

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Published inCHEMOTHERAPY Vol. 41; no. Supplement4; pp. 547 - 550
Main Authors Wada, Kouichi, Sega, Hiroyuki, Yosikawa, Hiroko, Arakawa, Masaaki
Format Journal Article
LanguageJapanese
Published Japanese Society of Chemotherapy 1993
Subjects
cefozopran
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Summary:We evaluated the clinical efficacy and safety of cefozopran, a new cephem antibiotics. Cefozopran was administered to 2 with bacteremia, 9 with respiratory tract infection. The patients received the drug, intravenously, for 5 to 15 days in dose of 0.5-2.0 g/day. Clinical effects were excellent in 1, good in 9, poor in 1. As side effects, Clostridium difficile-induced colitis occurred in one patient. Abnormal laboratory findings were transient elevation of transaminases in two cases.
ISSN:0009-3165
1884-5894
DOI:10.11250/chemotherapy1953.41.Supplement4_547