A Cured Case of Adult Respiratory Distress Syndrome Caused by Septicemia of Staphylococcus Aureus

• Published in: Nihon Kyōbu Shikkan Gakkai zasshi Vol. 27; no. 12; pp. 1551 - 1555
• Main Authors: Sakamoto, Koya, Houya, Isao, Nagata, Makoto, Kuramitsu, Kaoru, Kiuchi, Hidenori, Sakamoto, Yosio, Yamamoto, Keiichiro, Dohi, Yutaka
• Format: Journal Article
• Language: Japanese
• Published: Japan The Japanese Respiratory Society 01.12.1989
• Subjects: Adult; Adult respiratory distress syndrome; Anti-Bacterial Agents; Corticosteroid; Drug Therapy, Combination - therapeutic use; Female; Glycoproteins - therapeutic use; Humans; Methylprednisolone - therapeutic use; Positive-Pressure Respiration; Pregnancy; Puerperal Infection - complications; Puerperal Infection - drug therapy; Respiratory Distress Syndrome, Adult - etiology; Respiratory Distress Syndrome, Adult - therapy; Sepsis - complications; Sepsis - drug therapy; Staphylococcal Infections - complications; Staphylococcal Infections - drug therapy; Staphylococcus aureus; Trypsin Inhibitors - therapeutic use; Urinastatin
• ISSN: 0301-1542; 1883-471X
• DOI: 10.11389/jjrs1963.27.1551

A 33-year-old woman was admitted as an emergency case because of shock condition after delivery. Physical examination revealed fever, cyanosis and coarse crackles throughout the entire chest. Laboratory data showed leukocytosis and increase of CRP value. Adult respiratory distress syndrome (ARDS) was diagnosed based on progressive severe hypoxemia and bilateral diffuse alveolar shadows on chest X-ray film. The cause of ARDS was considered to be septicemia as staphylococcus aureus was cultured from lochia. The patient was intubated, then artificially ventilated employing PEEP. Chemotherapy using three different kinds of antibiotics was started, combined with the administration of corticosteroid and a protease inhibitor, Urinastatin. The patient finally recovered completely.