ASSOCIATION OF ACTIVE PULMONARY TUBERCULOSIS AND MALIGNANT DISEASES: A CLINICAL STUDY

• Published in: Kekkaku Vol. 70; no. 4; pp. 281 - 284
• Main Authors: MOURI, Masashi, MACHIDA, Kazuko, OOTSUKA, Yoshirou, SATOU, Kouji, KATAYAMA, Tooru, KOMATSU, Hikotarou, AKAGAWA, Shinobu, KURASHIMA, Atsuyuki, SHISHIDO, Harumi, KAWABE, Yoshiko, SAKAMOTO, Eriko, NAGAYAMA, Naohiro, NAGAI, Hideaki, SAGARA, Yuuzou, FUKUSHIMA, Kanae
• Format: Journal Article
• Language: Japanese
• Published: Japan JAPANESE SOCIETY FOR TUBERCULOSIS 01.04.1995
• Subjects: Active pulmonary tuberculosis; Adult; Aged; Aged, 80 and over; Clinical study; Female; Humans; Male; Malignant tumor; Middle Aged; Neoplasms - complications; Tuberculosis, Pulmonary - complications
• ISSN: 0022-9776; 1884-2410
• DOI: 10.11400/kekkaku1923.70.281

The association of pulmonary tuberculosis and bronchogenic carcinoma has beenreported by many authors, however, there are rather few studies about the association ofpulmonary tuberculosis and other malignant diseases and how the latter affects theoutcome of the former. Between 1980 and 1993, we had in our hospital 104 patients who had both activepulmonary tuberculosis and malignant diseases. Pulmonary tuberculosis was diagnosed at the time or after the diagnosis of malignant diseases in 74 patients, of whom 92% (68patients) were males and 42% (31 patients) were over the age of 70. There were 23 stomachcancer (31%), and 15 lung cancer (20%). In 11 patients tuberculosis developed after theinitiation of radiation and/or chemotherapy. 67 patients could be followed up for morethan 6 months after the initiation of chemotherapy for tuberculosis and the negativeconversion rate was as high as 95.5% at 3 months. The fact indicates that the association of malignant diseases dose not influence thecourse of tuberculosis and that these patients could be treated safely in general hospitals, provided the diagnosis is made properly without unnecessary delay.