FK 037の泌尿器科領域感染症に対する前期第II相試験成績
新しい注射用セフェム剤FK 037の泌尿器科領域感染症に対する臨床効果と安全性を予備的に検討した。対象は尿路に基礎疾患を有するカテーテル非留置の複雑性尿路感染症で, 15歳以上80歳未満の入院患者とした。用法・用量は1回0.5g (力価), 1.0g (力価) または2.0g (力価) を朝・夕の1日2回, 5～9日間点滴静注し, UTI薬効評価基準に従い臨床効果を判定した。UTI薬効評価基準に合致した32例における臨床効果は著効15例, 有効15例, 無効2例で有効率は93.8%であった。副作用は1例に発疹がみられ, 臨床検査値の異常変動は1例に軽度のGPT上昇が認められたのみであった。以上...
Saved in:
| Published in | CHEMOTHERAPY Vol. 42; no. 9; pp. 1036 - 1047 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
公益社団法人 日本化学療法学会
1994
|
| Online Access | Get full text |
| ISSN | 0009-3165 1884-5894 |
| DOI | 10.11250/chemotherapy1953.42.1036 |
Cover
| Abstract | 新しい注射用セフェム剤FK 037の泌尿器科領域感染症に対する臨床効果と安全性を予備的に検討した。対象は尿路に基礎疾患を有するカテーテル非留置の複雑性尿路感染症で, 15歳以上80歳未満の入院患者とした。用法・用量は1回0.5g (力価), 1.0g (力価) または2.0g (力価) を朝・夕の1日2回, 5～9日間点滴静注し, UTI薬効評価基準に従い臨床効果を判定した。UTI薬効評価基準に合致した32例における臨床効果は著効15例, 有効15例, 無効2例で有効率は93.8%であった。副作用は1例に発疹がみられ, 臨床検査値の異常変動は1例に軽度のGPT上昇が認められたのみであった。以上の成績から, 本剤はグラム陽性菌からグラム陰性菌まで幅広い抗菌スペクトルを有しており, これを反映して臨床試験においても優れた効果を示し, 安全性も特に問題がないことから, 泌尿器科領域感染症に対して有用性が期待される薬剤であると考えられる。 |
|---|---|
| AbstractList | 新しい注射用セフェム剤FK 037の泌尿器科領域感染症に対する臨床効果と安全性を予備的に検討した。対象は尿路に基礎疾患を有するカテーテル非留置の複雑性尿路感染症で, 15歳以上80歳未満の入院患者とした。用法・用量は1回0.5g (力価), 1.0g (力価) または2.0g (力価) を朝・夕の1日2回, 5～9日間点滴静注し, UTI薬効評価基準に従い臨床効果を判定した。UTI薬効評価基準に合致した32例における臨床効果は著効15例, 有効15例, 無効2例で有効率は93.8%であった。副作用は1例に発疹がみられ, 臨床検査値の異常変動は1例に軽度のGPT上昇が認められたのみであった。以上の成績から, 本剤はグラム陽性菌からグラム陰性菌まで幅広い抗菌スペクトルを有しており, これを反映して臨床試験においても優れた効果を示し, 安全性も特に問題がないことから, 泌尿器科領域感染症に対して有用性が期待される薬剤であると考えられる。 |
| Author | 斎藤, 功 熊本, 悦明 河村, 信夫 熊澤, 淨一 河田, 幸道 守殿, 貞夫 大森, 弘之 |
| Author_xml | – sequence: 1 fullname: 熊本, 悦明 organization: 札幌医科大学医学部泌尿器科学教室 – sequence: 1 fullname: 斎藤, 功 organization: 東京共済病院泌尿器科 – sequence: 1 fullname: 河田, 幸道 organization: 岐阜大学医学部泌尿器科学教室 – sequence: 1 fullname: 守殿, 貞夫 organization: 神戸大学医学部泌尿器科学教室 – sequence: 1 fullname: 大森, 弘之 organization: 岡山大学医学部泌尿器科学教室 – sequence: 1 fullname: 熊澤, 淨一 organization: 九州大学医学部泌尿器科学教室 – sequence: 1 fullname: 河村, 信夫 organization: 東海大学医学部泌尿器科学教室 |
| BookMark | eNpdkL1Kw1AAhS9SwVr7DvoAqfc3vXeUYrVacdE53Jvc2Jb-kXTpWBFUVFA6aFGIk1YsKrh0qg8Tkti3UKmDuJyzHD443yJINVtNDcAKgjmEMIOrdkU3Wp2K9mS7iwQjOYpzCBJzDqQR59RgXNAUSEMIhUGQyRZA1verCkKEoIk5ToOt4vYyJPmw9xK_n0dvH9FgmDxeTe9voiCIj4I46CfXx2HvOXqdhL1BeHgWnV7Ed0EyGpVKye348-lhOuzHJ5fJeLIE5l1Z93X2tzNgv7i-V9g0yrsbpcJa2ahhkoeGFNxkSjg20lwyh3LXpZi61BUKIYG55kw6VCKhMaJKcZtyCRWmmmmoyPe7DNiZcWt-Rx5oq-1VG9LrWtLrVO26tv5LsSi2xCx-3PzZSc-qSfIFeBd6sw |
| ContentType | Journal Article |
| Copyright | 社団法人日本化学療法学会 |
| Copyright_xml | – notice: 社団法人日本化学療法学会 |
| DOI | 10.11250/chemotherapy1953.42.1036 |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 1884-5894 |
| EndPage | 1047 |
| ExternalDocumentID | article_chemotherapy1953_42_9_42_9_1036_article_char_ja |
| GroupedDBID | 53G ADBBV ALMA_UNASSIGNED_HOLDINGS BAWUL DIK JSF JSH KQ8 RJT RZJ ZOHVM |
| ID | FETCH-LOGICAL-j2370-a9865b9dc1e8a5d48ff424f4f9b11928e85ad4a19e214bb8c48a0b24e5e0b3103 |
| ISSN | 0009-3165 |
| IngestDate | Wed Sep 03 06:08:41 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Issue | 9 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j2370-a9865b9dc1e8a5d48ff424f4f9b11928e85ad4a19e214bb8c48a0b24e5e0b3103 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/chemotherapy1953/42/9/42_9_1036/_article/-char/ja |
| PageCount | 12 |
| ParticipantIDs | jstage_primary_article_chemotherapy1953_42_9_42_9_1036_article_char_ja |
| PublicationCentury | 1900 |
| PublicationDate | 19940000 |
| PublicationDateYYYYMMDD | 1994-01-01 |
| PublicationDate_xml | – year: 1994 text: 19940000 |
| PublicationDecade | 1990 |
| PublicationTitle | CHEMOTHERAPY |
| PublicationTitleAlternate | CHEMOTHERAPY |
| PublicationYear | 1994 |
| Publisher | 公益社団法人 日本化学療法学会 |
| Publisher_xml | – name: 公益社団法人 日本化学療法学会 |
| References | 4) Mine Y, et al.: In vivo antibacterial activity of FK 037, a novel parenteral broad-spectrum cephalosporin. J Antibiot 46: 88-98, 1993 21) Naide Y, et al.: Comparative study of cefpirome and ceftazidime in complicated urinary tract infections. Acta Urologica Japonica 37: 447-464, 1991 (in Japanese 16) Matsumoto T, Kumazawa J: Evaluation of drug efficacy for catheterized patients. Antibiot & Chemother 6: 2137-2144, 1990 (in Japanese 1) Mine, Y, et al.: In vitro antibacterial activity of FK 037, a novel parenteral broad-spectrum cephalosporin. J Antibiot 46: 71-87, 1993 9) Yokota T, Suzuki E: A new, improved parenteral cephem antibiotic-FK 037, its in vitro antibacterial activity. Program and Abstracts No.853, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 2) Ohki H, Kawabata K, Okuda S, Kamimura T, Sakane K: FK 037, a new parenteral cephalosporin with a broad antibacterial spectrum. J Antibiot 46: 359-361, 1993 8) Mine Y, Sakamoto H, Hatano K, Higashi Y, Kamimura T, Matsumoto F, Kuwahara S: FK 037, a novel parenteral broad-spectrum cephalosporin: IV. Animal pharmacokinetics Program and Abstracts No.852, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 22) Kumazawa J, et al.: Dose-finding study of cefe. pime for the treatment of complicated urinary tract infections. Nishinihon J Urol 54: 285-298, 1992 (in Japanese 5) Mine Y, Watanabe Y, Sakamoto H, Hatano K, Kamimura T, Matsumoto F, Kuwahara S: FK 037, A novel parenteral broad-spectrum cephalosporin: I. In vitro antibacterial activity. Program and Abstracts No.849, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 20) Naide Y, et al.: Dose-finding study of HR810 (cefpirome) in complicated urinary tract infections. Chemotherapy (Tokyo) 39: 158-173, 1991 (in Javanese 25) Kumazawa J, et al.: Comparative study of cefclidin and ceftazidime for the treatment of complicated urinary tract infections. Nishinihon J Urol 54: 1435-1460, 1992 (in Japanese 3) Mine, Y, et al.: Excellent activity of FK 037, a novel parenteral broad-spectrum cephalosporin, against methicillin-resistant staphylococci. J Antibiot 46: 99-119, 1993 24) Kumazawa J, et al.: Clinical evaluation of cefclidin for the treatment of complicated urinary tract infections.-Dote-finding study using ceftazidime as a reference drug-.Nishinihon J Urol 54: 528-549, 1992 (in Japanese 12) Goto S, Higashi 5, Miyazaki S, Kaneko Y, Yamaguchi K: FK 037, a New Parenteral Cephalosporin: In vitro and in vivo antibacterial activity. Program and Abstracts No.856, 31 at Interscience Conference on Antimicrobial Agents and Chemotherapy, 1991 15) Nakashima M, Uematsu T, Takiguchi Y, Obara M, Terakawa M: Pharmacokinetics and safety of FK 037 in healthy volunteers. Program and Abstracts, No.883, 33 rd Interscience Conference on Antimicrobial Agents and Chemotherapy, New Orleans, 1993 6) Mine Y, Watanabe Y, Sakamoto H, Kamimura T, Tawara S, Matsumoto F, Kuwahara S. FK 037, a novel parenteral broad-spectrum cephalosporin: II. In vivo antibacterial activity. Program and Abstracts No.850, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 23) Kumazawa J, et al.: Comparative study of cefepime vs ceftazidime for the treatment of complicated urinary tract infections. Nishinihon J Urol 54: 974-985, 1992 (in Japanese 13) Nishino T, Otsuki M, Nishihara Y: In vitro and in vivo antibacterial activities of FK 037, a new broad-spectrum cephalosporin. Program and Abstracts No.857, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 18) UTI Committee (Chairman: Ohkoshi M): Criteria for evaluation of clinical efficacy of antimicrobial agents on urinary tract infection (Third edition). Chemotherapy (Tokyo) 34: 408-441, 1986 (in Japanese 10) Inoue K, Hamana Y, Mitsuhashi S: In vitro antibacterial activity of FK 037, a new cephalosporin. Program and Abstracts No.854, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 11) Ueno K, Watanabe K, Kato N, Muto Y, Bandoh K, Oka M: Comparative in vitro activity of FK 037, a novel cephalosporin, and other related agents against anaerobic bacteria. Program and Abstracts No.855, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 19) Deputy Director, New Drugs Division Pharmaceutical Affairs Bureau Ministry of Health & Welfare Japan: General consideration for the clinical evaluation of new drugs. Clin Eval 20: 401-411, 1992 (in Japanese 7) Mine Y, Watanabe Y, Sakamoto H, Kamimura T, Matsumoto F, Kuwahara S: FK 037, A novel parenteral broad-spectrum cephalosporin: III. Excellent activity against methicillin-resistant Staphylococci. Program and Abstracts No.851, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 17) Japan Society of Chemotherapy: A method for determining the minimum inhibitory concentration of antimicrobial agents (3 rd edition). Chemotherapy (Tokyo) 29: 76-79, 1981 (in Japanese 14) FK 037 Toxicology Studies-The Reports of Fujisawa Pharmaceutical Co. Ltd. |
| References_xml | – reference: 1) Mine, Y, et al.: In vitro antibacterial activity of FK 037, a novel parenteral broad-spectrum cephalosporin. J Antibiot 46: 71-87, 1993 – reference: 13) Nishino T, Otsuki M, Nishihara Y: In vitro and in vivo antibacterial activities of FK 037, a new broad-spectrum cephalosporin. Program and Abstracts No.857, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 4) Mine Y, et al.: In vivo antibacterial activity of FK 037, a novel parenteral broad-spectrum cephalosporin. J Antibiot 46: 88-98, 1993 – reference: 8) Mine Y, Sakamoto H, Hatano K, Higashi Y, Kamimura T, Matsumoto F, Kuwahara S: FK 037, a novel parenteral broad-spectrum cephalosporin: IV. Animal pharmacokinetics Program and Abstracts No.852, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 24) Kumazawa J, et al.: Clinical evaluation of cefclidin for the treatment of complicated urinary tract infections.-Dote-finding study using ceftazidime as a reference drug-.Nishinihon J Urol 54: 528-549, 1992 (in Japanese) – reference: 21) Naide Y, et al.: Comparative study of cefpirome and ceftazidime in complicated urinary tract infections. Acta Urologica Japonica 37: 447-464, 1991 (in Japanese) – reference: 14) FK 037 Toxicology Studies-The Reports of Fujisawa Pharmaceutical Co. Ltd. – reference: 18) UTI Committee (Chairman: Ohkoshi M): Criteria for evaluation of clinical efficacy of antimicrobial agents on urinary tract infection (Third edition). Chemotherapy (Tokyo) 34: 408-441, 1986 (in Japanese) – reference: 16) Matsumoto T, Kumazawa J: Evaluation of drug efficacy for catheterized patients. Antibiot & Chemother 6: 2137-2144, 1990 (in Japanese) – reference: 7) Mine Y, Watanabe Y, Sakamoto H, Kamimura T, Matsumoto F, Kuwahara S: FK 037, A novel parenteral broad-spectrum cephalosporin: III. Excellent activity against methicillin-resistant Staphylococci. Program and Abstracts No.851, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 9) Yokota T, Suzuki E: A new, improved parenteral cephem antibiotic-FK 037, its in vitro antibacterial activity. Program and Abstracts No.853, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 12) Goto S, Higashi 5, Miyazaki S, Kaneko Y, Yamaguchi K: FK 037, a New Parenteral Cephalosporin: In vitro and in vivo antibacterial activity. Program and Abstracts No.856, 31 at Interscience Conference on Antimicrobial Agents and Chemotherapy, 1991 – reference: 22) Kumazawa J, et al.: Dose-finding study of cefe. pime for the treatment of complicated urinary tract infections. Nishinihon J Urol 54: 285-298, 1992 (in Japanese) – reference: 20) Naide Y, et al.: Dose-finding study of HR810 (cefpirome) in complicated urinary tract infections. Chemotherapy (Tokyo) 39: 158-173, 1991 (in Javanese) – reference: 6) Mine Y, Watanabe Y, Sakamoto H, Kamimura T, Tawara S, Matsumoto F, Kuwahara S. FK 037, a novel parenteral broad-spectrum cephalosporin: II. In vivo antibacterial activity. Program and Abstracts No.850, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 17) Japan Society of Chemotherapy: A method for determining the minimum inhibitory concentration of antimicrobial agents (3 rd edition). Chemotherapy (Tokyo) 29: 76-79, 1981 (in Japanese) – reference: 11) Ueno K, Watanabe K, Kato N, Muto Y, Bandoh K, Oka M: Comparative in vitro activity of FK 037, a novel cephalosporin, and other related agents against anaerobic bacteria. Program and Abstracts No.855, 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 5) Mine Y, Watanabe Y, Sakamoto H, Hatano K, Kamimura T, Matsumoto F, Kuwahara S: FK 037, A novel parenteral broad-spectrum cephalosporin: I. In vitro antibacterial activity. Program and Abstracts No.849, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 10) Inoue K, Hamana Y, Mitsuhashi S: In vitro antibacterial activity of FK 037, a new cephalosporin. Program and Abstracts No.854, 31 st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 1991 – reference: 15) Nakashima M, Uematsu T, Takiguchi Y, Obara M, Terakawa M: Pharmacokinetics and safety of FK 037 in healthy volunteers. Program and Abstracts, No.883, 33 rd Interscience Conference on Antimicrobial Agents and Chemotherapy, New Orleans, 1993 – reference: 2) Ohki H, Kawabata K, Okuda S, Kamimura T, Sakane K: FK 037, a new parenteral cephalosporin with a broad antibacterial spectrum. J Antibiot 46: 359-361, 1993 – reference: 23) Kumazawa J, et al.: Comparative study of cefepime vs ceftazidime for the treatment of complicated urinary tract infections. Nishinihon J Urol 54: 974-985, 1992 (in Japanese) – reference: 19) Deputy Director, New Drugs Division Pharmaceutical Affairs Bureau Ministry of Health & Welfare Japan: General consideration for the clinical evaluation of new drugs. Clin Eval 20: 401-411, 1992 (in Japanese) – reference: 25) Kumazawa J, et al.: Comparative study of cefclidin and ceftazidime for the treatment of complicated urinary tract infections. Nishinihon J Urol 54: 1435-1460, 1992 (in Japanese) – reference: 3) Mine, Y, et al.: Excellent activity of FK 037, a novel parenteral broad-spectrum cephalosporin, against methicillin-resistant staphylococci. J Antibiot 46: 99-119, 1993 |
| SSID | ssib001106282 ssj0000626693 ssib058492509 ssib005879733 ssib008506721 |
| Score | 1.2788473 |
| Snippet | 新しい注射用セフェム剤FK 037の泌尿器科領域感染症に対する臨床効果と安全性を予備的に検討した。対象は尿路に基礎疾患を有するカテーテル非留置の複雑性尿路感染症で, 15歳以上80歳未満の入院患者とした。用法・用量は1回0.5g (力価), 1.0g (力価) または2.0g (力価) を朝・夕の1日2回,... |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 1036 |
| Title | FK 037の泌尿器科領域感染症に対する前期第II相試験成績 |
| URI | https://www.jstage.jst.go.jp/article/chemotherapy1953/42/9/42_9_1036/_article/-char/ja |
| Volume | 42 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | CHEMOTHERAPY, 1994/09/25, Vol.42(9), pp.1036-1047 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrR1Na9RANNQK4kUUFb9ZwTlJ1nxMMjPHZDtht8VPWugtJNnksGCV0h70VhFUVFB60KKwnrRiUcFLT_WneFh21_4L35ukSSoVtAghzM687zfZeTPJvNG0SzwzU4a72-2uk-g0YlSPooTrLGGM2UmSxhmud1y95rbn6PS8Mz9x4Eftq6XlpbiZ3N9zX8l-vAp14FfcJfsPni2JQgWUwb9wBw_D_a98HMxcxs3s0oZ4kHiSSJf4UG4R6RDfIH6ABSGIx4lkxGNEmETCT4MIrpoCvACL06KANTYCC0Z4SdlHYC8gvixqgCYWLMJVExeETyn0lqIDvFpwdTqKkk984MaJB5xdxZ8rJsAWCgbCAIAv63EyZmq4PtuWt7wbZayNgByQvIIT8ID-oehYirKLanFZwUMFNEpkDvp4NId3kIQI6mC-hYZDYSkargDzhZJcKI3tCt5BW4PsgAgFsLKC50hFSNVMwWbVegomRi77vuLvoPC5bVAdJZuvUKHGswtHCodIqPfgUmqiDk6lPBJqoYbIcUpZgKFnwBoVftkEhADY2zVKwbNj5mdoNNN8YOKc6g4vxC1GLmrVnlBRG4ZMw3ZrIQ2m49h7uIQAGDo5_D3cLvb73cPXqk1qNSsSu7KRF309_B0lpFYo8htihhVctBj2YAJz0GLMxG9uZ27WXtOauIW3li-OM8Fq8w9Mp1jL3wfBsgCJRbmICtiuK8rTEtFmh7SLO5pd-ZNeEG32YO61892mCiVnj2pHijlgw8uFP6ZN9KLj2nQw04CHebDyefTt2fDr9-Ha-vjDy-13r4f9_uhhf9RfHb96NFj5NPyyNVhZGzx4OnzyfPS2P97Y6HTGbzZ_fny_vb46evxivLl1QpsL5GyrrRcHneg9y2aGHgnuOrHoJmbKI6dLeZZRi2Y0E7EJMzCecifq0sgUqWXSOOYJ5ZERWzR1UiPGgwJPapMLdxbSU1oDYpssEUAhdQ0aJSKGcNOKUyuCeYadJelpLchVD-_m2WzCfXr0zP8idFY7nOcnx2XNc9rk0uJyeh4C_aX4guosvwC8_tK2 |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=FK+037%E3%81%AE%E6%B3%8C%E5%B0%BF%E5%99%A8%E7%A7%91%E9%A0%98%E5%9F%9F%E6%84%9F%E6%9F%93%E7%97%87%E3%81%AB%E5%AF%BE%E3%81%99%E3%82%8B%E5%89%8D%E6%9C%9F%E7%AC%ACII%E7%9B%B8%E8%A9%A6%E9%A8%93%E6%88%90%E7%B8%BE&rft.jtitle=CHEMOTHERAPY&rft.au=%E7%86%8A%E6%9C%AC%2C+%E6%82%A6%E6%98%8E&rft.au=%E6%96%8E%E8%97%A4%2C+%E5%8A%9F&rft.au=%E6%B2%B3%E7%94%B0%2C+%E5%B9%B8%E9%81%93&rft.au=%E5%AE%88%E6%AE%BF%2C+%E8%B2%9E%E5%A4%AB&rft.date=1994&rft.pub=%E5%85%AC%E7%9B%8A%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E5%8C%96%E5%AD%A6%E7%99%82%E6%B3%95%E5%AD%A6%E4%BC%9A&rft.issn=0009-3165&rft.eissn=1884-5894&rft.volume=42&rft.issue=9&rft.spage=1036&rft.epage=1047&rft_id=info:doi/10.11250%2Fchemotherapy1953.42.1036&rft.externalDocID=article_chemotherapy1953_42_9_42_9_1036_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0009-3165&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0009-3165&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0009-3165&client=summon |