膵・消化管神経内分泌腫瘍の疫学の動向

• Published in: 日本内分泌・甲状腺外科学会雑誌 Vol. 31; no. 4; pp. 279 - 283
• Main Authors: 中村, 和彦, 伊藤, 鉄英, 奥坂, 拓志, 今村, 正之, 李, 倫學, 河本, 泉, 肱岡, 真之, 五十嵐, 久人, 河邉, 顕, 島津, 章
• Format: Journal Article
• Language: Japanese
• Published: 日本内分泌外科学会・日本甲状腺外科学会 2014
• Subjects: 全国疫学調査; 消化管神経内分泌腫瘍; 神経内分泌腫瘍; 膵内分泌腫瘍
• ISSN: 2186-9545
• DOI: 10.11226/jaesjsts.31.4_279

There have been few epidemiological data on gastroenteropancreatic neuroendocrine tumors (GEPNETs) in Japan. First, we reported the epidemiology of pancreatic endocrine tumors (PNETs) and gastrointestinal neuroendocrine tumors (GI-NETs) in Japan in 2005. Next, we conducted the second survey regarding with GEPNETs patients who received treatment in 2010. A total of 3,379 individuals received treatment for PNETs in 2010. The number of patients in 2010 was an increase of about 1.2 times as compared to that in 2005. Non-functioning tumor (NF)-PNET constituted 64.5％, followed by insulinoma (20.9％) and gastrinoma (8.2％). On the other hand, an estimated 8,088 patients received treatment for GI-NETs. The number of patients in 2010 was an increase of about 1.8 times as compared to that in 2005. The locations of GI-NETs varied: foregut, 26.1％; midgut, 3.6％; and hindgut, 70.3％. The frequency of carcinoid syndrome in GI-NETs was only 3.2％. The results show that the number of Japanese patients with GEP-NET in 2010 was an increase compared in 2005.