開口障害および視覚障害を呈した巨細性動脈炎の1例

• Published in: 日本口腔外科学会雑誌 Vol. 64; no. 11; pp. 650 - 654
• Main Authors: 足立, 健, 町田, 好聡, 山本, 学, 下里, 剛史, 浅田, 泰幸, 渡邊, 裕加
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.11.2018
• Subjects: ステロイドパルス療法; 巨細胞性動脈炎; 浅側頭動脈; 視覚障害; 開口障害
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.64.650

Giant cell arteritis (GCA) is a disease entity characterized by histopathological findings of granuloma formation with giant cells in arterial walls. It causes dysfunction of several important organs secondary to stenosis or obstruction of the affected vasculature. We treated a 76 -year old woman who presented with trismus and facial pain during jaw movements. She additionally had marked fatigue and masticatory muscle pain, and her maximum jaw range of motion was 30 mm. Both superficial arteries were swollen. She also complained of visual impairment in that the lower part of her right visual field would darken for several seconds. After a biopsy of the superficial artery, she was given a histopathological diagnosis of GCA. She fulfilled the GCA diagnostic criteria established by the Ministry of Health of Japan, a specific disease research group, and the American Association of Rheumatology. Pulse steroid therapy was administered in the Department of Neurology, and her symptoms markedly improved. She has shown good progress since then.