多発性骨髄腫に移行した下顎骨孤立性形質細胞腫の1例

• Published in: 日本口腔外科学会雑誌 Vol. 65; no. 2; pp. 110 - 114
• Main Authors: 富岡, 寛文, 濱本, 正太郎, 横川, 美咲, 原田, 浩之, 生田, 稔, 坂本, 啓
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.02.2019
• Subjects: 下顎枝; 多発性骨髄腫; 孤立性形質細胞腫
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.65.110

We report a case of solitary plasmacytoma in the mandibular ramus that transformed into multiple myeloma. The patient was an 81-year-old man who had been aware of a left preauricular mass and was referred to our department in August 2012. A diffuse, elastic and slightly-hard tumor was recognized in the left preauricular region. Panoramic radiography showed multilocular and indistinctly circumscribed bone resorption from the left mandibular ramus to the condylar process. On computed tomography, a indistinctly circumscribed oval lesion was observed at the same region. Fine needle aspiration cytology showed proliferation of plasma cells, and the lesion was diagnosed as a IgA- λ type solitary plasmacytoma, because no evidence of multiple myeloma was found on general examination. The patient received radiotherapy; however, after 11 months the lesion transformed into multiple myeloma. Chemotherapy was administered, and complete remission was obtained. There has been no recurrence for 4 years 1 months.