入院下に埋伏智歯抜歯を行ったグルコーストランスポーター1欠損症患者の1例

• Published in: 日本口腔外科学会雑誌 Vol. 66; no. 8; pp. 366 - 370
• Main Authors: 鵜澤, 成一, 元木, 彩子, 濱田, 正和, 清水, 英孝, 西山, 今日子, 由良, 義明
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.08.2020
• Subjects: グルコーストランスポーター1欠損症; ケトン食; 智歯抜歯
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.66.366

Glucose transporter 1 (GLUT-1) deficiency is a rare metabolic disorder of the brain caused by mutations of GLUT-1 gene and inefficient use of glucose. In this disease, ketogenic diet therapy is necessary to supply ketone bodies instead of glucose as the energy source of the brain. We report a patient with GLUT-1 deficiency who was hospitalized and underwent third molar extraction. This is the first such report in the field of oral and maxillofacial surgery. There was no problem with preoperative starvation testing. Therefore, we performed the operation with the patient under general anesthesia. His teeth were extracted successfully without any complications such as convulsive attacks, hypoglycemia, or unexpected blood levels of ketone bodies. When we treat patients with GLUT-1 deficiency, it is important to closely cooperate with pediatricians, anesthesiologists, pharmacists, and dieticians in the perioperative management of patients.