舌癌術後に頸部リンパ節転移が疑われたRosai-Dorfman病の1例

Rosai-Dorfman disease (RDD) is a rare non-neoplastic disorder that is characterized by the proliferation of histiocytes, mostly in the lymph nodes. We report a case of RDD that was initially suspected to be cervical lymph node metastasis after surgery for tongue cancer. An 80-year-old male patient h...

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Published in日本口腔外科学会雑誌 Vol. 67; no. 5; pp. 303 - 308
Main Authors 髙橋, 望, 山本, 達郎, 廣末, 晃之, 村端, 由希, 中山, 秀樹, 郷原, 俊輔
Format Journal Article
LanguageJapanese
Published 社団法人 日本口腔外科学会 20.05.2021
Subjects
Rosai-Dorfman病
リンパ節転移疑い
口腔癌
頸部リンパ節
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.67.303

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Abstract Rosai-Dorfman disease (RDD) is a rare non-neoplastic disorder that is characterized by the proliferation of histiocytes, mostly in the lymph nodes. We report a case of RDD that was initially suspected to be cervical lymph node metastasis after surgery for tongue cancer. An 80-year-old male patient had undergone radical surgery including a left partial glossectomy, left neck dissection, and forearm flap reconstruction for cancer involving the left side of his tongue, and was followed up for 2 years. Thereafter, enlarged lymph nodes in the right submandibular area were revealed on CT and neck ultrasonography. After systemic scrutiny, he underwent a right neck dissection resulting in a diagnosis of cervical lymph node metastasis. However, a postoperative histopathological examination revealed no cervical lymph node metastasis, and he was diagnosed with RDD by immunohistochemical staining. More than three years after the right neck dissection, the patient’s condition is favorable, with no evidence of recurrence.
AbstractList Rosai-Dorfman disease (RDD) is a rare non-neoplastic disorder that is characterized by the proliferation of histiocytes, mostly in the lymph nodes. We report a case of RDD that was initially suspected to be cervical lymph node metastasis after surgery for tongue cancer. An 80-year-old male patient had undergone radical surgery including a left partial glossectomy, left neck dissection, and forearm flap reconstruction for cancer involving the left side of his tongue, and was followed up for 2 years. Thereafter, enlarged lymph nodes in the right submandibular area were revealed on CT and neck ultrasonography. After systemic scrutiny, he underwent a right neck dissection resulting in a diagnosis of cervical lymph node metastasis. However, a postoperative histopathological examination revealed no cervical lymph node metastasis, and he was diagnosed with RDD by immunohistochemical staining. More than three years after the right neck dissection, the patient’s condition is favorable, with no evidence of recurrence.
Author 中山, 秀樹
郷原, 俊輔
村端, 由希
髙橋, 望
山本, 達郎
廣末, 晃之
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References 7) 宇於崎宏， 鹿島健司， 他： 鼻腔腫瘤で発症したRosai-Dorfman diseaseの1例．日臨細胞会誌 39: 340-342, 2000.
25) 小亀敏明， 大江秀一， 他：【頸部・項部の皮膚病】＜臨床例＞ Rosai-Dorfman病．皮病診療 40: 257-260, 2018.
20) 真田朋昌， 清水義貴， 他： 声門に病変を生じたRosai-Dorfman病の1例．耳鼻・頭頸外科 88: 67-70, 2016.
8) 米原修治：Rosai-Dorfman病の1例．診断病理 18: 207-209, 2001.
10) 新宅雅幸， 山名則和：髄膜Rosai-Dorfman病の1例．診断病理 20: 94-97, 2003.
2) Foucar E, Rosai J, et al : Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease)： review of the entity. Semin Diagn Pathol 7: 19-73, 1990.
18) 高木秀雄， 西尾　仁， 他：肝門部リンパ節にRosai-Dorfman病類似組織像を認めた肝細胞癌の1例．日消誌 109: 1213-1222, 2012.
4) Rosai J and Dorfman RF : Sinus histiocytosis with massive lymphadenopathy. A pseudolymphomatous benign disorder．Analysis of 34 cases. Cancer 30: 1174-1188, 1972.
29) Lima FB, Barcelos PS, et al : Rosai-Dorfman disease with spontaneous resolution: case report of a child. Rev Bras Hematol Hemoter 33: 312-314, 2011.
26) 横井　共， 阿部　厚， 他：頸部リンパ節転移におけるPETの診断精度および病理組織学的所見について．日口外誌 56: 409-415, 2010.
15) 魲　成隆， 藤井直子， 他：Rosai-Dorfman Diseaseの1例．映像情報Med 40: 86-87, 2008.
16) 石原園子， 本田由美， 他：肝腫瘤として発症したextranodal Rosai-Dorfman diseaseの1例．診断病理 25: 36-39, 2008.
11) 鈴木教之， 藤田直昭， 他：Cutaneous Rosai-Dorfman diseaseの1例．Skin Cancer 19: 124-127, 2004.
1) Rosai J and Dorfman RF : Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity. Arch Pathol 87: 63-70, 1969.
6) 宮崎眞和， 北村溥之， 他：Sinus histiocytosis with massive lymphadenopathyの1例．天理医紀 1: 97-101, 1998.
17) 一色裕之， 林　敏昭， 他：リンパ節腫脹なしに複数の節外病変を認めたRosai-Dorfman病．綜合臨 59: 2021-2023, 2010.
21) 水口聖哉， 中野万里子， 他：対側乳腺に微小浸潤癌を伴った乳腺発生Rosai-Dorfman 病の1例．日臨細胞会誌 55: 329-333, 2016.
27) Pulsoni A, Anghel G, et al : Treatment of Sinus Histiocytosis With Massive Lymphadenopathy (Rosai-Dorfman Disease): Report of a Case and Literature Review. Am J Hematol 69: 67-71, 2002.
19) 今井みどり， 藤田　勝， 他： 髄膜腫を疑われたRosai-Dorfman diseaseの一例．岡山臨細胞会誌 33: 42-45, 2014.
5) Juskevicius R and Finley JL : Rosai-Dorfman disease of the parotid gland : cytologic and histopathologic findings with immunohistochemical correlation. Arch Pathol Lab Med 125: 1348-1350, 2001.
13) 岩朝光利， 土持廣仁， 他：髄膜腫と鑑別が困難であった多発性頭蓋内Rosai-Dorfman diseaseの1例．脳神外ジャーナル 16: 127-133, 2007.
24) 松井祐興， 鈴木　豊， 他：頸部リンパ節と胸椎生検から診断したRosai-Dorfman病例．耳鼻臨床 111: 133-138, 2018.
9) 田邉　豊， 田川京子， 他：末梢性顔面神経麻痺を初期症状とした肥厚性硬膜炎を伴ったRosai-Dorfman病．麻酔 51: 1129-1131, 2002.
23) 北村真悠， 山田茂憲， 他：皮膚Rosai-Dorfman病の1例．臨皮 72: 41-45, 2018.
3) Andriko JAW, Morrison A, et al : Rosai-Dorfman disease isolated to the central nervous system. A report of 11 cases. Mod Pathol 14: 172-178, 2001
22) 森　俊輔， 宮村和也， 他：著明な炎症高値を呈しステロイド療法が奏功したRosai-Dorfman病の1例．臨リウマチ 29: 197-204, 2017.
28) Dalia S, Sagatys E, et al : Rosai-Dorfman Disease: Tumor Biology, Clinical Features, Pathology, and Treatment. Cancer Control 21: 322-327, 2014.
12) 渡辺次郎， 植山雅彦， 他：脊椎硬膜外に限局したRosai-Dorfman病の1例． 診断病理 23: 299-302, 2006.
14) 村上洋嗣， 宮本　豊， 他：Extranodal Rosai-Dorfman病の1例．西日泌 69: 253-256, 2007.
References_xml – reference: 7) 宇於崎宏， 鹿島健司， 他： 鼻腔腫瘤で発症したRosai-Dorfman diseaseの1例．日臨細胞会誌 39: 340-342, 2000.
– reference: 23) 北村真悠， 山田茂憲， 他：皮膚Rosai-Dorfman病の1例．臨皮 72: 41-45, 2018.
– reference: 11) 鈴木教之， 藤田直昭， 他：Cutaneous Rosai-Dorfman diseaseの1例．Skin Cancer 19: 124-127, 2004.
– reference: 26) 横井　共， 阿部　厚， 他：頸部リンパ節転移におけるPETの診断精度および病理組織学的所見について．日口外誌 56: 409-415, 2010.
– reference: 3) Andriko JAW, Morrison A, et al : Rosai-Dorfman disease isolated to the central nervous system. A report of 11 cases. Mod Pathol 14: 172-178, 2001．
– reference: 15) 魲　成隆， 藤井直子， 他：Rosai-Dorfman Diseaseの1例．映像情報Med 40: 86-87, 2008.
– reference: 1) Rosai J and Dorfman RF : Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity. Arch Pathol 87: 63-70, 1969.
– reference: 18) 高木秀雄， 西尾　仁， 他：肝門部リンパ節にRosai-Dorfman病類似組織像を認めた肝細胞癌の1例．日消誌 109: 1213-1222, 2012.
– reference: 27) Pulsoni A, Anghel G, et al : Treatment of Sinus Histiocytosis With Massive Lymphadenopathy (Rosai-Dorfman Disease): Report of a Case and Literature Review. Am J Hematol 69: 67-71, 2002.
– reference: 10) 新宅雅幸， 山名則和：髄膜Rosai-Dorfman病の1例．診断病理 20: 94-97, 2003.
– reference: 21) 水口聖哉， 中野万里子， 他：対側乳腺に微小浸潤癌を伴った乳腺発生Rosai-Dorfman 病の1例．日臨細胞会誌 55: 329-333, 2016.
– reference: 29) Lima FB, Barcelos PS, et al : Rosai-Dorfman disease with spontaneous resolution: case report of a child. Rev Bras Hematol Hemoter 33: 312-314, 2011.
– reference: 6) 宮崎眞和， 北村溥之， 他：Sinus histiocytosis with massive lymphadenopathyの1例．天理医紀 1: 97-101, 1998.
– reference: 25) 小亀敏明， 大江秀一， 他：【頸部・項部の皮膚病】＜臨床例＞ Rosai-Dorfman病．皮病診療 40: 257-260, 2018.
– reference: 19) 今井みどり， 藤田　勝， 他： 髄膜腫を疑われたRosai-Dorfman diseaseの一例．岡山臨細胞会誌 33: 42-45, 2014.
– reference: 9) 田邉　豊， 田川京子， 他：末梢性顔面神経麻痺を初期症状とした肥厚性硬膜炎を伴ったRosai-Dorfman病．麻酔 51: 1129-1131, 2002.
– reference: 20) 真田朋昌， 清水義貴， 他： 声門に病変を生じたRosai-Dorfman病の1例．耳鼻・頭頸外科 88: 67-70, 2016.
– reference: 22) 森　俊輔， 宮村和也， 他：著明な炎症高値を呈しステロイド療法が奏功したRosai-Dorfman病の1例．臨リウマチ 29: 197-204, 2017.
– reference: 14) 村上洋嗣， 宮本　豊， 他：Extranodal Rosai-Dorfman病の1例．西日泌 69: 253-256, 2007.
– reference: 5) Juskevicius R and Finley JL : Rosai-Dorfman disease of the parotid gland : cytologic and histopathologic findings with immunohistochemical correlation. Arch Pathol Lab Med 125: 1348-1350, 2001.
– reference: 12) 渡辺次郎， 植山雅彦， 他：脊椎硬膜外に限局したRosai-Dorfman病の1例． 診断病理 23: 299-302, 2006.
– reference: 8) 米原修治：Rosai-Dorfman病の1例．診断病理 18: 207-209, 2001.
– reference: 13) 岩朝光利， 土持廣仁， 他：髄膜腫と鑑別が困難であった多発性頭蓋内Rosai-Dorfman diseaseの1例．脳神外ジャーナル 16: 127-133, 2007.
– reference: 28) Dalia S, Sagatys E, et al : Rosai-Dorfman Disease: Tumor Biology, Clinical Features, Pathology, and Treatment. Cancer Control 21: 322-327, 2014.
– reference: 4) Rosai J and Dorfman RF : Sinus histiocytosis with massive lymphadenopathy. A pseudolymphomatous benign disorder．Analysis of 34 cases. Cancer 30: 1174-1188, 1972.
– reference: 24) 松井祐興， 鈴木　豊， 他：頸部リンパ節と胸椎生検から診断したRosai-Dorfman病例．耳鼻臨床 111: 133-138, 2018.
– reference: 16) 石原園子， 本田由美， 他：肝腫瘤として発症したextranodal Rosai-Dorfman diseaseの1例．診断病理 25: 36-39, 2008.
– reference: 2) Foucar E, Rosai J, et al : Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease)： review of the entity. Semin Diagn Pathol 7: 19-73, 1990.
– reference: 17) 一色裕之， 林　敏昭， 他：リンパ節腫脹なしに複数の節外病変を認めたRosai-Dorfman病．綜合臨 59: 2021-2023, 2010.
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SubjectTerms Rosai-Dorfman病
リンパ節転移疑い
口腔癌
頸部リンパ節
Title 舌癌術後に頸部リンパ節転移が疑われたRosai-Dorfman病の1例
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