舌癌術後に頸部リンパ節転移が疑われたRosai-Dorfman病の1例

• Published in: 日本口腔外科学会雑誌 Vol. 67; no. 5; pp. 303 - 308
• Main Authors: 髙橋, 望, 廣末, 晃之, 村端, 由希, 郷原, 俊輔, 山本, 達郎, 中山, 秀樹
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.05.2021
• Subjects: Rosai-Dorfman病; リンパ節転移疑い; 口腔癌; 頸部リンパ節
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.67.303

Rosai-Dorfman disease (RDD) is a rare non-neoplastic disorder that is characterized by the proliferation of histiocytes, mostly in the lymph nodes. We report a case of RDD that was initially suspected to be cervical lymph node metastasis after surgery for tongue cancer. An 80-year-old male patient had undergone radical surgery including a left partial glossectomy, left neck dissection, and forearm flap reconstruction for cancer involving the left side of his tongue, and was followed up for 2 years. Thereafter, enlarged lymph nodes in the right submandibular area were revealed on CT and neck ultrasonography. After systemic scrutiny, he underwent a right neck dissection resulting in a diagnosis of cervical lymph node metastasis. However, a postoperative histopathological examination revealed no cervical lymph node metastasis, and he was diagnosed with RDD by immunohistochemical staining. More than three years after the right neck dissection, the patient’s condition is favorable, with no evidence of recurrence.